|+1 404 474 4654|
|+1 888 205 9894 (TF)|
TAF7 RNA Polymerase II, TATA Box Binding Protein (TBP)-Associated Factor, 55kDa (TAF7) antibody
|Synonyms||TAF2F, TAFII55, 55kDa, Taf2f, AI607308, BB007175, MGC86629, CHUNP6888, MGC174760|
Alternatives ELISA, Western Blotting (WB)
|5 references available|
|Price||450.00 $ Plus shipping costs $45.00|
|Availability||Will be delivered in 2 to 3 Business Days|
|Immunogen||TAF7 (AAH32737, 130 a.a. ~ 224 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 K|
|Description||Other names: TAF2F, TAFII55 TAF7 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 55kDa|
|Characteristics||Purified Mouse Monoclonal Antibody (Mab)|
|Specificity||TAF7 (AAH32737, 130 a.a. ~ 224 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.|
|Molecular Weight||40259 DA|
Background: The intronless gene for this transcription coactivator is located between the protocadherin beta and gamma gene clusters on chromosome 5. The protein encoded by this gene is a component of the TFIID protein complex, a complex which binds to the TATA box in class II promoters and recruits RNA polymerase II and other factors. This particular subunit interacts with the largest TFIID subunit, as well as multiple transcription activators. The protein is required for transcription by promoters targeted by RNA polymerase II.
|Application Notes||ELISA ~~ 1ug/ml~3ng/ml Western blot ~~ 1:500~1000|
|Buffer||Clear, colorless solution in phosphate buffered saline, pH 7.2 .|
|Storage||Maintain refrigerated at 2-8 deg C for up to 6 months. For long term storage store at -20 deg C in small aliquots to prevent freeze-thaw cycles|
|Research Area||Cell Structure, Transcription Factors, Signaling|
|Restrictions||For Research Use only|
Olsen, Blagoev, Gnad et al.: "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks." in: Cell, Vol. 127, Issue 3, pp. 635-48, 2006 (PubMed).
Hartman, Walters, Hentosh: "Presence of the anti-leukemic nucleotide analog, 2-chloro-2'-deoxyadenosine-5'-monophosphate, in a promoter sequence alters DNA binding of TATA-binding protein (TBP)." in: Archives of biochemistry and biophysics, Vol. 459, Issue 2, pp. 223-32, 2007 (PubMed).
Jeronimo, Forget, Bouchard et al.: "Systematic analysis of the protein interaction network for the human transcription machinery reveals the identity of the 7SK capping enzyme." in: Molecular cell, Vol. 27, Issue 2, pp. 262-74, 2007 (PubMed).
Barbe, Lundberg, Oksvold et al.: "Toward a confocal subcellular atlas of the human proteome." in: Molecular & cellular proteomics : MCP, Vol. 7, Issue 3, pp. 499-508, 2008 (PubMed).
Gegonne, Weissman, Lu et al.: "TFIID component TAF7 functionally interacts with both TFIIH and P-TEFb." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 105, Issue 14, pp. 5367-72, 2008 (PubMed).
|Hosts||Rabbit (13), Mouse (2)|
|Reactivities||Human (14), Mouse (Murine) (5), Rat (Rattus) (5), Cow (Bovine) (2), Dog (Canine) (1), Xenopus laevis (1), Zebrafish (1)|
|Applications||Western Blotting (WB) (13), ELISA (9), Immunohistochemistry (IHC) (8), Immunofluorescence (IF) (2), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (2)|
|Epitopes||C-Term (1), Internal Region (1), N-Term (1)|