LIM Homeobox 1 (LHX1) (AA 1-101) antibody

Details for Product No. ABIN394340, Supplier: Log in to see
Antigen
  • LIM-1
  • LIM1
  • lim-1
  • lim1
  • xlim-1
  • Lim-1
  • Lim1
  • lmx2
  • LHX1
  • wu:fe25d04
  • wu:fj36b06
  • LIM homeobox 1
  • LIM homeobox 1a
  • LIM homeobox protein 1
  • LHX1
  • Lhx1
  • lhx1
  • lhx1a
Epitope
AA 1-101
19
14
13
7
6
3
2
2
1
1
1
1
1
1
Reactivity
Human
72
19
14
5
4
4
3
3
2
2
2
2
2
2
1
1
1
1
Host
Mouse
46
26
Clonality (Clone)
Monoclonal ()
Application
ELISA
53
32
23
17
17
16
5
2
2
1
1
1
Options
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Immunogen LHX1 (NP_005559, 1 a.a. ~ 101 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 K
Clone 4D1
Isotype IgG2a kappa
Specificity LHX1 (NP_005559, 1 a.a. ~ 101 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Purification This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
Alternative Name LHX1 (LHX1 Antibody Abstract)
Background Synonyms: Serine protease inhibitor J6, 47 kDa heat shock protein, Collagen-binding protein, Colligin, Serpin H1,Hsp47, Cbp1, Serpinh1
Molecular Weight 44808 DA
Gene ID 12406
NCBI Accession NP_005559
Research Area Transcription Factors, Signaling, Cell Structure
Application Notes ELISA ~~ 1ug/ml~3ng/ml
Comment

Background: This gene encodes a member of a large protein family which contains the LIM domain, a unique cysteine-rich zinc-binding domain. The encoded protein may function as a transcriptional regulator and be involved in control of differentiation and development of neural and lymphoid cells. A similar protein in mice is an essential regulator of the vertebrate head organizer.

Restrictions For Research Use only
Buffer PBS with 0.09% (w/v) sodium azide.
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles
Expiry Date 6 months
Supplier Images
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) image for anti-LIM Homeobox 1 (LHX1) (AA 1-101) antibody (ABIN394340) Immunoperoxidase of monoclonal antibody to LHX1 on formalin-fixed paraffin-embedded h...
Immunohistochemistry (IHC) image for anti-LIM Homeobox 1 (LHX1) (AA 1-101) antibody (ABIN394340) anti-LIM Homeobox 1 (LHX1) (AA 1-101) antibody (Image 2)
Background publications Christopoulos, Gazouli, Fotopoulou, Creatsas: "The role of genes in the development of Mullerian anomalies: where are we today?" in: Obstetrical & gynecological survey, Vol. 64, Issue 11, pp. 760-8, 2009 (PubMed).

Avraham, Hadas, Vald, Zisman, Schejter, Visel, Klar: "Transcriptional control of axonal guidance and sorting in dorsal interneurons by the Lim-HD proteins Lhx9 and Lhx1." in: Neural development, Vol. 4, pp. 21, 2009 (PubMed).

Poché, Kwan, Raven, Furuta, Reese, Behringer: "Lim1 is essential for the correct laminar positioning of retinal horizontal cells." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 27, Issue 51, pp. 14099-107, 2007 (PubMed).

Zody, Garber, Adams, Sharpe, Harrow, Lupski, Nicholson, Searle, Wilming, Young, Abouelleil, Allen, Bi, Bloom, Borowsky, Bugalter, Butler, Chang, Chen, Cook, Corum, Cuomo, de Jong, DeCaprio, Dewar et al.: "DNA sequence of human chromosome 17 and analysis of rearrangement in the human lineage. ..." in: Nature, Vol. 440, Issue 7087, pp. 1045-9, 2006 (PubMed).

Gerhard, Wagner, Feingold, Shenmen, Grouse, Schuler, Klein, Old, Rasooly, Good, Guyer, Peck, Derge, Lipman, Collins, Jang, Sherry, Feolo, Misquitta, Lee, Rotmistrovsky, Greenhut, Schaefer, Buetow et al.: "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). ..." in: Genome research, Vol. 14, Issue 10B, pp. 2121-7, 2004 (PubMed).