You are viewing an incomplete version of our website. Please click to reload the website as full version.

Zinc Finger Protein ZIC 1 (ZIC1) (AA 2-95) antibody

Details for Product No. ABIN394343, Supplier: Log in to see
Antigen
  • ZIC
  • ZNF201
  • opl
Epitope
AA 2-95
18
14
14
9
5
2
1
1
1
1
Reactivity
Human
59
18
13
Host
Mouse
36
22
2
1
Clonality (Clone)
Monoclonal ()
Conjugate
Un-conjugated
3
2
2
2
2
2
1
1
1
1
1
1
1
1
1
Application
ELISA, Western Blotting (WB)
50
35
11
4
4
3
3
1
1
Supplier
Log in to see
Supplier Product No.
Log in to see
Request

Showcase your results, aid the scientific community, and receive a full refund.

Contribute a validation

Learn more

Available images

Immunogen ZIC1 (NP_003403, 2 a.a. ~ 95 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 K
Clone 4D11
Isotype IgG2b kappa
Specificity ZIC1 (NP_003403, 2 a.a. ~ 95 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Purification This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
Alternative Name ZIC1 (ZIC1 Antibody Abstract)
Background Synonyms: Serine protease inhibitor J6, 47 kDa heat shock protein, Collagen-binding protein, Colligin, Serpin H1,Hsp47, Cbp1, Serpinh1
Molecular Weight 48295 DA
Gene ID 12406
NCBI Accession NP_003403
Research Area Cancer, Transcription Factors, Signaling, Cell Structure
Application Notes ELISA ~~ 1ug/ml~3ng/ml Western blot ~~ 1:500~1000
Comment

Background: This gene encodes a member of the ZIC family of C2H2-type zinc finger proteins. Members of this family are important during development. Aberrant expression of this gene is seen in medulloblastoma, a childhood brain tumor. This gene is closely linked to the gene encoding zinc finger protein of the cerebellum 4, a related family member on chromosome 3. This gene encodes a transcription factor that can bind and transactivate the apolipoprotein E gene.

Restrictions For Research Use only
Buffer PBS with 0.09% (w/v) sodium azide.
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles
Expiry Date 6 months
Supplier Images
ELISA image for anti-Zinc Finger Protein ZIC 1 (ZIC1) (AA 2-95) antibody (ABIN394343) Detection limit for recombinant GST tagged ZIC1 is approximately 1 ng/mL as a capture...
Background publications Wang, Jin, Wang et al.: "ZIC1 is downregulated through promoter hypermethylation in gastric cancer." in: Biochemical and biophysical research communications, Vol. 379, Issue 4, pp. 959-63, 2009 (PubMed).

Baranzini, Wang, Gibson et al.: "Genome-wide association analysis of susceptibility and clinical phenotype in multiple sclerosis...." in: Human molecular genetics, Vol. 18, Issue 4, pp. 767-78, 2009 (PubMed).

Arora, Dutkiewicz, Scaria et al.: "Inhibition of translation in living eukaryotic cells by an RNA G-quadruplex motif." in: RNA (New York, N.Y.), Vol. 14, Issue 7, pp. 1290-6, 2008 (PubMed).

Barbe, Lundberg, Oksvold et al.: "Toward a confocal subcellular atlas of the human proteome." in: Molecular & cellular proteomics : MCP, Vol. 7, Issue 3, pp. 499-508, 2008 (PubMed).

Pourebrahim, Van Dam, Bauters et al.: "ZIC1 gene expression is controlled by DNA and histone methylation in mesenchymal proliferations." in: FEBS letters, Vol. 581, Issue 26, pp. 5122-6, 2007 (PubMed).