Forkhead Box A1 (FOXA1) antibody

Details for Product No. ABIN394359
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Antigen
Synonyms
HNF3A, TCF3A, Hnf3a, Tcf3a, Hnf-3a, Tcf-3a, fkd7, forkhead-7, HNF-3a, HNF3-alpha, HNF3alpha, fkh2, foxa1, hnf3a, tFoxA1, tcf3a, FoxA4a, XFD-1, fkh1, pintallavis, xfkh1, xkfh-1, xfkh2, fkh, FOXA1, Ci-f ... show more
HNF3A, TCF3A, Hnf3a, Tcf3a, Hnf-3a, Tcf-3a, fkd7, forkhead-7, HNF-3a, HNF3-alpha, HNF3alpha, fkh2, foxa1, hnf3a, tFoxA1, tcf3a, FoxA4a, XFD-1, fkh1, pintallavis, xfkh1, xkfh-1, xfkh2, fkh, FOXA1, Ci-fkh, foxa3, Foxa1 show less
Reactivity
Human
(76), (13), (10), (6), (3), (3), (3), (2), (1)
Host
Mouse
(38), (30), (10)
Clonality (Clone)
Monoclonal ()
Application
Immunofluorescence (IF), Western Blotting (WB)
(60), (40), (39), (16), (6), (3), (3), (2), (1)
Pubmed 5 references available
Catalog no. ABIN394359
Quantity 0.1 mg
Price
450.00 $   Plus shipping costs $45.00
Options
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Availability Will be delivered in 2 to 3 Business Days

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  • +1 404 474 4654
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Immunogen FOXA1 (NP_004487, 367 a.a. ~ 473 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 K
Clone 4F6
Isotype IgG2b kappa
Specificity FOXA1 (NP_004487, 367 a.a. ~ 473 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Purification This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
Alternative Name FOXA1
Background Synonyms: Serine protease inhibitor J6, 47 kDa heat shock protein, Collagen-binding protein, Colligin, Serpin H1,Hsp47, Cbp1, Serpinh1
Molecular Weight 49321 DA
Gene ID 12406
UniProt NP_004487
Research Area Transcription Factors, Signaling, Chromatin, Metabolism, Cell Structure
Application Notes Western blot = 1:500-1000
Comment

Background: This gene encodes a member of the forkhead class of DNA-binding proteins. These hepatocyte nuclear factors are transcriptional activators for liver-specific transcripts such as albumin and transthyretin, and they also interact with chromatin. Similar family members in mice have roles in the regulation of metabolism and in the differentiation of the pancreas and liver.

Restrictions For Research Use only
Concentration 1 mg/ml
Buffer PBS with 0.09% (w/v) sodium azide.
Preservative Sodium azide
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles
Expiry Date 6 months
Supplier Images
anti-Forkhead Box A1 (FOXA1) antibody Immunofluorescence of monoclonal antibody to FOXA1 on A-431 cell (antibody concentration 10 µg/mL). FOXA1 monoclonal antibody (M03), clone 4F6 Western Blot analysis of FOXA1 expression in A-431.
anti-Forkhead Box A1 (FOXA1) antibody (2) anti-Forkhead Box A1 (FOXA1) antibody (Image 2)
Background publications Sano, Aoyagi, Takahashi et al.: "Forkhead box A1 transcriptional pathway in KRT7-expressing esophageal squamous cell carcinomas with extensive lymph node metastasis." in: International journal of oncology, Vol. 36, Issue 2, pp. 321-30, 2009 (PubMed).

Zhang, Ali, Zhou et al.: "ErbB3 binding protein 1 represses metastasis-promoting gene anterior gradient protein 2 in prostate cancer." in: Cancer research, Vol. 70, Issue 1, pp. 240-8, 2010 (PubMed).

Song, Washington, Crawford: "Loss of FOXA1/2 is essential for the epithelial-to-mesenchymal transition in pancreatic cancer." in: Cancer research, Vol. 70, Issue 5, pp. 2115-25, 2010 (PubMed).

Bernardo, Lozada, Miedler et al.: "FOXA1 is an essential determinant of ERalpha expression and mammary ductal morphogenesis." in: Development (Cambridge, England), Vol. 137, Issue 12, pp. 2045-54, 2010 (PubMed).

Liu, Niu, Wang et al.: "[Diagnostic and prognostic significance of FOXA1 expression in molecular subtypes of breast invasive ductal carcinomas]." in: Zhonghua yi xue za zhi, Vol. 90, Issue 20, pp. 1403-7, 2010 (PubMed).

Hosts (38), (30), (10)
Reactivities (76), (13), (10), (6), (3), (3), (3), (2), (1)
Applications (60), (40), (39), (16), (6), (3), (3), (2), (1)
Epitopes (15), (8), (6), (4), (3), (2), (2), (2), (2), (1), (1), (1), (1), (1)
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