NAD Synthetase 1 (NADSYN1) antibody

Antigen: NAD Synthetase 1 (NADSYN1)

Synonyms: FLJ10631, FLJ36703, FLJ40627, 9130012B15Rik, NADSYN1, MGC127343, zgc:165489

Clonality: Monoclonal (4G9)

Host: Mouse

Reactivity: Human

Application: ELISA, Western Blotting (WB)

Certificates: ISO 9001:2008

Catalog no.: ABIN394369

Additional Information

Alternative name: NADSYN1

Gene ID: 55191

UniProt: NP_060631

Immunogen: NADSYN1 (-, 609 a.a. ~ 707 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 K

Isotype: IgG1 kappa

Clone: 4G9

Description: Other names: FLJ10631 NAD synthetase 1

Characteristics: Purified Mouse Monoclonal Antibody (Mab)

Specificity: NADSYN1 (-, 609 a.a. ~ 707 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Molecular Weight: 79294 DA

Comments:

Background: Nicotinamide adenine dinucleotide (NAD) is a coenzyme in metabolic redox reactions, a precursor for several cell signaling molecules, and a substrate for protein posttranslational modifications. NAD synthetase (EC 6.3.5.1) catalyzes the final step in the biosynthesis of NAD from nicotinic acid adenine dinucleotide (NaAD).

Application Details

Application Notes: ELISA ~~ 1ug/ml~3ng/ml Western blot ~~ 1:500~1000

Purification: Purified

Buffer: Clear, colorless solution in phosphate buffered saline, pH 7.2 .

Storage: Maintain refrigerated at 2-8 deg C for up to 6 months. For long term storage store at -20 deg C in small aliquots to prevent freeze-thaw cycles

Research Area: Translation Factors, Cell Signaling, Signaling, Metabolism, Cell Structure

Restrictions: For Research Use only

Images

NADSYN1 monoclonal antibody (M01), clone 4G9 Western Blot analysis of NADSYN1 expression in Hela NE ( Cat # L013V3 ).

Publications

Product: Oguri, Kato, Yokoi et al.: "Assessment of a polymorphism of SDK1 with hypertension in Japanese Individuals." in: American journal of hypertension, Vol. 23, Issue 1, pp. 70-7, 2009 (PubMed).

Talmud, Drenos, Shah et al.: "Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip." in: American journal of human genetics, Vol. 85, Issue 5, pp. 628-42, 2009 (PubMed).

Yoshida, Kato, Yokoi et al.: "Association of genetic variants with hemorrhagic stroke in Japanese individuals." in: International journal of molecular medicine, Vol. 25, Issue 4, pp. 649-56, 2010 (PubMed).

Ahn, Yu, Stolzenberg-Solomon et al.: "Genome-wide association study of circulating vitamin D levels." in: Human molecular genetics, Vol. 19, Issue 13, pp. 2739-45, 2010 (PubMed).

Bailey, Xie, Do et al.: "Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study." in: Diabetes Care, Vol. 33, Issue 10, pp. 2250-3, 2010 (PubMed).