LIM Domain Only 4 (LMO4) antibody

Antigen: LIM Domain Only 4 (LMO4)

Synonyms: LOC100217776

Clonality: Monoclonal (4H8)

Host: Mouse

Reactivity: Human

Conjugate: Un-conjugated

Application: ELISA, Western Blotting (WB)

Certificates: ISO 9001:2008

Catalog no.: ABIN394373

Additional Information

Alternative name: LMO4

Gene ID: 8543

Immunogen: LMO4 (AAH17673, 1 a.a. ~ 166 a.a) full length recombinant protein with GST tag. MW of the GST tag alone is 26 K

Isotype: IgG2a lambda

Clone: 4H8

Description: Other names: LIM domain only 4

Characteristics: Purified Mouse Monoclonal Antibody (Mab)

Specificity: LMO4 (AAH17673, 1 a.a. ~ 166 a.a) full length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Molecular Weight: 17994 DA

Comments:

Background: This gene encodes a cysteine-rich protein that contains two LIM domains but lacks a DNA-binding homeodomain. The encoded protein may play a role as a transcriptional regulator or as an oncogene.

Application Details

Application Notes: ELISA ~~ 1ug/ml~3ng/ml Western blot ~~ 1:500~1000

Purification: Purified

Buffer: Clear, colorless solution in phosphate buffered saline, pH 7.2 .

Storage: Maintain refrigerated at 2-8 deg C for up to 6 months. For long term storage store at -20 deg C in small aliquots to prevent freeze-thaw cycles

Research Area: Transcription Factors, Signaling, Cell Structure

Restrictions: For Research Use only

Images

Detection limit for recombinant GST tagged LMO4 is approximately 0.3ng/ml as a capture antibody.

Publications

Product: Yu, Ohuchida, Nakata et al.: "LIM only 4 is overexpressed in late stage pancreas cancer." in: Molecular cancer, Vol. 7, pp. 93, 2009 (PubMed).

Huang, Kawase-Koga, Zhang et al.: "Transcription factor Lmo4 defines the shape of functional areas in developing cortices and regulates sensorimotor control." in: Developmental biology, Vol. 327, Issue 1, pp. 132-42, 2009 (PubMed).

Caporaso, Gu, Chatterjee et al.: "Genome-wide and candidate gene association study of cigarette smoking behaviors." in: PLoS ONE, Vol. 4, Issue 2, pp. e4653, 2009 (PubMed).

Montañez-Wiscovich, Seachrist, Landis et al.: "LMO4 is an essential mediator of ErbB2/HER2/Neu-induced breast cancer cell cycle progression." in: Oncogene, Vol. 28, Issue 41, pp. 3608-18, 2009 (PubMed).

Ribasés, Bosch, Hervás et al.: "Case-control study of six genes asymmetrically expressed in the two cerebral hemispheres: association of BAIAP2 with attention-deficit/hyperactivity disorder." in: Biological psychiatry, Vol. 66, Issue 10, pp. 926-34, 2009 (PubMed).