Upstream Transcription Factor 2, C-Fos Interacting (USF2) (AA 1-101) antibody

Details for Product No. ABIN394409
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Antigen
Synonyms fip, MGC79773, bhlhb12, USF2, Usf-2, bHLHb12, FIP, fb12g11, si:dkey-211g8.3, wu:fb12g11, usf2
Epitope
AA 1-101
(11), (10), (8), (4), (4), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1)
Reactivity
Human
(68), (24), (23), (2), (1), (1), (1), (1)
Host
Mouse
(48), (23)
Clonality (Clone)
Monoclonal ()
Conjugate
Un-conjugated
(2), (2), (2), (2), (2), (2)
Application
Immunofluorescence (IF), Western Blotting (WB)
(63), (32), (23), (18), (10), (10), (4), (4), (3), (2), (1)
Pubmed 5 references available
Quantity 0.1 mg
Options
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Catalog No. ABIN394409
450.00 $
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Immunogen USF2 (NP_003358, 1 a.a. ~ 101 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 K
Clone 6A9
Isotype IgG2a kappa
Specificity USF2 (NP_003358, 1 a.a. ~ 101 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Purification This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
Alternative Name USF2
Background Synonyms: Serine protease inhibitor J6, 47 kDa heat shock protein, Collagen-binding protein, Colligin, Serpin H1,Hsp47, Cbp1, Serpinh1
Molecular Weight 36955 DA
Gene ID 12406
NCBI Accession NP_003358
Research Area Transcription Factors, Signaling, Cell Structure
Application Notes Western blot = 1:500-1000
Comment

Background: This gene encodes a member of the basic helix-loop-helix leucine zipper family, and can function as a cellular transcription factor. The encoded protein can activate transcription through pyrimidine-rich initiator (Inr) elements and E-box motifs. Two transcript variants encoding distinct isoforms have been identified for this gene.

Restrictions For Research Use only
Buffer PBS with 0.09% (w/v) sodium azide.
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles
Expiry Date 6 months
Supplier Images
anti-Upstream Transcription Factor 2, C-Fos Interacting (USF2) (AA 1-101) antibody Immunofluorescence of monoclonal antibody to USF2 on HeLa cell (antibody concentration 10 µg/mL). USF2 monoclonal antibody (M03), clone 6A9. Western Blot analysis of USF2 expression in different cell lines.
anti-Upstream Transcription Factor 2, C-Fos Interacting (USF2) (AA 1-101) antibody (2) anti-Upstream Transcription Factor 2, C-Fos Interacting (USF2) (AA 1-101) antibody (Image 2)
Background publications Agirre, Jiménez-Velasco, San José-Enériz et al.: "Down-regulation of hsa-miR-10a in chronic myeloid leukemia CD34+ cells increases USF2-mediated cell growth." in: Molecular cancer research : MCR, Vol. 6, Issue 12, pp. 1830-40, 2008 (PubMed).

Finotti, Treves, Zorzato et al.: "Upstream stimulatory factors are involved in the P1 promoter directed transcription of the A beta H-J-J locus." in: BMC molecular biology, Vol. 9, pp. 110, 2009 (PubMed).

Wang, Li, Zhang et al.: "HINT1 inhibits beta-catenin/TCF4, USF2 and NFkappaB activity in human hepatoma cells." in: International journal of cancer. Journal international du cancer, Vol. 124, Issue 7, pp. 1526-34, 2009 (PubMed).

Landa, Ruiz-Llorente, Montero-Conde et al.: "The variant rs1867277 in FOXE1 gene confers thyroid cancer susceptibility through the recruitment of USF1/USF2 transcription factors." in: PLoS genetics, Vol. 5, Issue 9, pp. e1000637, 2009 (PubMed).

Sun, Yu, Degraff et al.: "Upstream stimulatory factor 2, a novel FoxA1-interacting protein, is involved in prostate-specific gene expression." in: Molecular endocrinology (Baltimore, Md.), Vol. 23, Issue 12, pp. 2038-47, 2009 (PubMed).

Validation Images
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