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TBX2 antibody (T-Box 2) (AA 603-703)

Details for Product anti-TBX2 Antibody No. ABIN394433, Supplier: Login to see New
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Synonyms Xltbx2, tbx2, xtbx2, hm:zeh1581, tbx-c, tbxc, zeh1581, TBX2
AA 603-703
(15), (15), (10), (6), (5), (4), (4), (3), (2), (2), (1), (1), (1), (1), (1), (1), (1)
(64), (15), (8), (2), (2), (2), (1), (1), (1), (1)
(50), (15), (1)
Clonality (Clone)
Monoclonal ()
This TBX2 antibody is un-conjugated
(2), (2), (2), (2), (2), (2), (2)
Immunofluorescence (IF), Western Blotting (WB)
(51), (38), (13), (9), (6), (3), (3), (2), (2), (1)
Pubmed 5 references available
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Quantity 0.1 mg
Shipping to United States ( )
Availability Will be delivered in 8 to 11 Business Days
Immunogen TBX2 (NP_005985, 603 a.a. ~ 703 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 K
Clone 7G5
Isotype IgG3 kappa
Specificity TBX2 (NP_005985, 603 a.a. ~ 703 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Purification This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
Alternative Name TBX2 (TBX2 Antibody Abstract)
Background Synonyms: Serine protease inhibitor J6, 47 kDa heat shock protein, Collagen-binding protein, Colligin, Serpin H1,Hsp47, Cbp1, Serpinh1
Molecular Weight 74068 DA
Gene ID 12406
NCBI Accession NP_005985
Research Area Cancer, Transcription Factors, Signaling, Cell Structure
Pathways p53 Signaling
Application Notes Western blot = 1:500-1000

Background: This gene is a member of a phylogenetically conserved family of genes that share a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes. This gene product is the human homolog of mouse Tbx2, and shares strong sequence similarity with Drosophila omb protein. Expression studies indicate that this gene may have a potential role in tumorigenesis as an immortalizing agent. Transcript heterogeneity due to alternative polyadenylation has been noted for this gene.

Restrictions For Research Use only
Buffer PBS with 0.09% (w/v) sodium azide.
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles
Expiry Date 6 months
Supplier Images
Western Blotting (WB) image for anti-TBX2 antibody (T-Box 2) (AA 603-703) (ABIN394433) Immunofluorescence of monoclonal antibody to TBX2 on HeLa cell (antibody concentratio...
Immunohistochemistry (IHC) image for anti-TBX2 antibody (T-Box 2) (AA 603-703) (ABIN394433) anti-T-Box 2 (TBX2) (AA 603-703) antibody (Image 2)
Background publications Zhao, Li, Bradfield et al.: "The role of height-associated loci identified in genome wide association studies in the determination of pediatric stature." in: BMC medical genetics, Vol. 11, pp. 96, 2010 (PubMed).

Liu, Jiang, Zhang: "Expression of PSCA, PIWIL1, and TBX2 in endometrial adenocarcinoma." in: Onkologie, Vol. 33, Issue 5, pp. 241-5, 2010 (PubMed).

Abrahams, Parker, Prince: "The T-box transcription factor Tbx2: its role in development and possible implication in cancer." in: IUBMB life, Vol. 62, Issue 2, pp. 92-102, 2010 (PubMed).

Kim, Lee, Park et al.: "Identification of 15 loci influencing height in a Korean population." in: Journal of human genetics, Vol. 55, Issue 1, pp. 27-31, 2010 (PubMed).

Teng, Ballim, Mowla et al.: "Phosphorylation of histone H3 by protein kinase C signaling plays a critical role in the regulation of the developmentally important TBX2 gene." in: The Journal of biological chemistry, Vol. 284, Issue 39, pp. 26368-76, 2009 (PubMed).

Catalog No. ABIN394433
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