|+1 404 474 4654|
|+1 888 205 9894 (TF)|
Junctophilin 1 (JPH1) antibody
|Synonyms||JP1, JP-1, DKFZp762L0313, Jp1, ENSMUSG00000054314, JPH1, jph1, bZ1M12.3, si:rp71-1m12.3|
Alternatives ELISA, Western Blotting (WB)
|5 references available|
|Price||450.00 $ Plus shipping costs $45.00|
|Availability||Will be delivered in 2 to 3 Business Days|
|Immunogen||JPH1 (NP_065698, 501 a.a. ~ 580 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 K|
|Description||Other names: DKFZp762L0313, JP1, JP1 junctophilin 1|
|Characteristics||Purified Mouse Monoclonal Antibody (Mab)|
|Specificity||JPH1 (NP_065698, 501 a.a. ~ 580 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.|
|Molecular Weight||71686 DA|
Background: Junctional complexes between the plasma membrane and endoplasmic/sarcoplasmic reticulum are a common feature of all excitable cell types and mediate cross talk between cell surface and intracellular ion channels. The protein encoded by this gene is a component of junctional complexes and is composed of a C-terminal hydrophobic segment spanning the endoplasmic/sarcoplasmic reticulum membrane and a remaining cytoplasmic domain that shows specific affinity for the plasma membrane. This gene is a member of the junctophilin gene family.
|Application Notes||ELISA ~~ 1ug/ml~3ng/ml Western blot ~~ 1:500~1000|
|Buffer||Clear, colorless solution in phosphate buffered saline, pH 7.2 .|
|Storage||Maintain refrigerated at 2-8 deg C for up to 6 months. For long term storage store at -20 deg C in small aliquots to prevent freeze-thaw cycles|
|Research Area||Cell Structure|
|Restrictions||For Research Use only|
|Detection limit for recombinant GST tagged JPH1 is approximately 0.03ng/ml as a capture antibody.|
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Nusbaum, Mikkelsen, Zody et al.: "DNA sequence and analysis of human chromosome 8." in: Nature, Vol. 439, Issue 7074, pp. 331-5, 2006 (PubMed).
Olsen, Blagoev, Gnad et al.: "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks." in: Cell, Vol. 127, Issue 3, pp. 635-48, 2006 (PubMed).
Yamazaki, Yamazaki, Takeshima: "New molecular components supporting ryanodine receptor-mediated Ca(2+) release: roles of junctophilin and TRIC channel in embryonic cardiomyocytes." in: Pharmacology & therapeutics, Vol. 121, Issue 3, pp. 265-72, 2009 (PubMed).
Rose, Behm, Drgon et al.: "Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score." in: Molecular medicine (Cambridge, Mass.), Vol. 16, Issue 7-8, pp. 247-53, 2010 (PubMed).