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Armadillo Repeat Containing, X-Linked 1 (ARMCX1) (AA 188-296) antibody

Details for Product No. ABIN394684
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Antigen
Synonyms ARMCX1, DKFZp459J1211, ALEX1, 3010033I09Rik
Epitope
AA 188-296
(8), (6), (4), (2), (1), (1), (1)
Reactivity
Human
(28), (15), (14), (13), (13)
Host
Mouse
(27), (3)
Clonality (Clone)
Monoclonal ()
Conjugate
Un-conjugated
(2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application
ELISA, Western Blotting (WB)
(21), (10), (10), (3), (1)
Pubmed 5 references available
Quantity 0.1 mg
Options
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Catalog No. ABIN394684
450.00 $
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Immunogen ARMCX1 (NP_057692, 188 a.a. ~ 296 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 K
Clone 6E10
Isotype IgG3 kappa
Specificity ARMCX1 (NP_057692, 188 a.a. ~ 296 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Purification This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
Alternative Name ARMCX1
Background Synonyms: Serine protease inhibitor J6, 47 kDa heat shock protein, Collagen-binding protein, Colligin, Serpin H1,Hsp47, Cbp1, Serpinh1
Molecular Weight 49180 DA
Gene ID 12406
UniProt NP_057692
Research Area Cell Structure, Cancer
Application Notes ELISA ~~ 1ug/ml~3ng/ml Western blot ~~ 1:500~1000
Comment

Background: This gene encodes a member of the ALEX family of proteins and may play a role in tumor suppression. The encoded protein contains a potential N-terminal transmembrane domain and two Armadillo (arm) repeats. Other proteins containing the arm repeat are involved in development, maintenance of tissue integrity, and tumorigenesis. This gene is closely localized with other family members, including ALEX2 and ALEX3, on the X chromosome.

Restrictions For Research Use only
Buffer PBS with 0.09% (w/v) sodium azide.
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles
Expiry Date 6 months
Supplier Images
anti-Armadillo Repeat Containing, X-Linked 1 (ARMCX1) (AA 188-296) antibody Detection limit for recombinant GST tagged ARMCX1 is approximately 0.03 ng/mL as a capture antibody.
Background publications Ota, Suzuki, Nishikawa et al.: "Complete sequencing and characterization of 21,243 full-length human cDNAs." in: Nature genetics, Vol. 36, Issue 1, pp. 40-5, 2003 (PubMed).

Gerhard, Wagner, Feingold et al.: "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)." in: Genome research, Vol. 14, Issue 10B, pp. 2121-7, 2004 (PubMed).

Ross, Grafham, Coffey et al.: "The DNA sequence of the human X chromosome." in: Nature, Vol. 434, Issue 7031, pp. 325-37, 2005 (PubMed).

Otsuki, Ota, Nishikawa et al.: "Signal sequence and keyword trap in silico for selection of full-length human cDNAs encoding secretion or membrane proteins from oligo-capped cDNA libraries." in: DNA research : an international journal for rapid publication of reports on genes and genomes, Vol. 12, Issue 2, pp. 117-26, 2005 (PubMed).

Iseki, Takeda, Andoh et al.: "Human Arm protein lost in epithelial cancers, on chromosome X 1 (ALEX1) gene is transcriptionally regulated by CREB and Wnt/beta-catenin signaling." in: Cancer science, Vol. 101, Issue 6, pp. 1361-6, 2010 (PubMed).

Validation Images
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