Lipase, Endothelial (LIPG) antibody

Antigen: Lipase, Endothelial (LIPG)

Synonyms: EL, EDL, PRO719, MGC55345, zgc:55345, MGC69106, LIPG, lipe

Clonality: Monoclonal (1E11)

Host: Mouse

Reactivity: Human

Conjugate: Un-conjugated

Application: ELISA, Western Blotting (WB)

Certificates: ISO 9001:2008

Catalog no.: ABIN394686

Additional Information

Alternative name: LIPG

Gene ID: 9388

Immunogen: LIPG (AAH60825, 21 a.a. ~ 501 a.a) full length recombinant protein with GST tag. MW of the GST tag alone is 26 K

Isotype: IgG2a kappa

Clone: 1E11

Description: Other names: EDL, EL, PRO719 lipase, endothelial

Characteristics: Purified Mouse Monoclonal Antibody (Mab)

Specificity: LIPG (AAH60825, 21 a.a. ~ 501 a.a) full length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Molecular Weight: 56795 DA

Comments:

Background: The protein encoded by this gene has substantial phospholipase activity and may be involved in lipoprotein metabolism and vascular biology. This protein is designated a member of the TG lipase family by its sequence and characteristic lid region which provides substrate specificity for enzymes of the TG lipase family.

Application Details

Application Notes: ELISA ~~ 1ug/ml~3ng/ml Western blot ~~ 1:500~1000

Purification: Purified

Buffer: Clear, colorless solution in phosphate buffered saline, pH 7.2 .

Storage: Maintain refrigerated at 2-8 deg C for up to 6 months. For long term storage store at -20 deg C in small aliquots to prevent freeze-thaw cycles

Research Area: Metabolism, Cell Structure

Restrictions: For Research Use only

Images

Detection limit for recombinant GST tagged LIPG is approximately 1ng/ml as a capture antibody.

Publications

Product: Fontaine-Bisson, Renström, Rolandsson et al.: "Evaluating the discriminative power of multi-trait genetic risk scores for type 2 diabetes in a northern Swedish population." in: Diabetologia, Vol. 53, Issue 10, pp. 2155-62, 2010 (PubMed).

Ruaño, Thompson, Kane et al.: "Physiogenomic analysis of statin-treated patients: domain-specific counter effects within the ACACB gene on low-density lipoprotein cholesterol?" in: Pharmacogenomics, Vol. 11, Issue 7, pp. 959-71, 2010 (PubMed).

Huang, Qian, Li et al.: "Role of endothelial lipase in atherosclerosis." in: Translational research : the journal of laboratory and clinical medicine, Vol. 156, Issue 1, pp. 1-6, 2010 (PubMed).

Bailey, Xie, Do et al.: "Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study." in: Diabetes Care, Vol. 33, Issue 10, pp. 2250-3, 2010 (PubMed).

Hu, Lui, Mak et al.: "Pharmacogenetic analysis of lipid responses to rosuvastatin in Chinese patients." in: Pharmacogenetics and genomics, Vol. 20, Issue 10, pp. 634-7, 2010 (PubMed).