Lipase, Endothelial (LIPG) antibody

Details for Product No. ABIN394686
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Antigen
Synonyms EL, EDL, PRO719, LIPG, mEDL, lipase, 3110013K01Rik, zgc:55345, MGC69106, lipe
Reactivity
Human
(119), (31), (28), (14), (14), (13), (12), (2), (1), (1)
Host
Mouse
(68), (57), (5)
Clonality (Clone)
Monoclonal ()
Conjugate
Un-conjugated
(4), (4), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2)
Application
ELISA, Western Blotting (WB)
(100), (35), (33), (30), (29), (22), (19), (17), (7), (6), (3), (3), (1)
Pubmed 5 references available
Catalog no. ABIN394686
Quantity 0.1 mg
Price
450.00 $   Plus shipping costs $45.00
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Immunogen LIPG (AAH60825, 21 a.a. ~ 501 a.a) full length recombinant protein with GST tag. MW of the GST tag alone is 26 K
Clone 1E11
Isotype IgG2a kappa
Specificity LIPG (AAH60825, 21 a.a. ~ 501 a.a) full length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Purification This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
Alternative Name LIPG
Background Synonyms: Serine protease inhibitor J6, 47 kDa heat shock protein, Collagen-binding protein, Colligin, Serpin H1,Hsp47, Cbp1, Serpinh1
Molecular Weight 56795 DA
Gene ID 12406
Research Area Metabolism, Cell Structure
Application Notes ELISA ~~ 1ug/ml~3ng/ml Western blot ~~ 1:500~1000
Comment

Background: The protein encoded by this gene has substantial phospholipase activity and may be involved in lipoprotein metabolism and vascular biology. This protein is designated a member of the TG lipase family by its sequence and characteristic lid region which provides substrate specificity for enzymes of the TG lipase family.

Restrictions For Research Use only
Buffer PBS with 0.09% (w/v) sodium azide.
Preservative Sodium azide
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles
Expiry Date 6 months
Supplier Images
anti-Lipase, Endothelial (LIPG) antibody Detection limit for recombinant GST tagged LIPG is approximately 1 ng/mL as a capture antibody.
Background publications Fontaine-Bisson, Renström, Rolandsson et al.: "Evaluating the discriminative power of multi-trait genetic risk scores for type 2 diabetes in a northern Swedish population." in: Diabetologia, Vol. 53, Issue 10, pp. 2155-62, 2010 (PubMed).

Ruaño, Thompson, Kane et al.: "Physiogenomic analysis of statin-treated patients: domain-specific counter effects within the ACACB gene on low-density lipoprotein cholesterol?" in: Pharmacogenomics, Vol. 11, Issue 7, pp. 959-71, 2010 (PubMed).

Huang, Qian, Li et al.: "Role of endothelial lipase in atherosclerosis." in: Translational research : the journal of laboratory and clinical medicine, Vol. 156, Issue 1, pp. 1-6, 2010 (PubMed).

Bailey, Xie, Do et al.: "Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study." in: Diabetes Care, Vol. 33, Issue 10, pp. 2250-3, 2010 (PubMed).

Hu, Lui, Mak et al.: "Pharmacogenetic analysis of lipid responses to rosuvastatin in Chinese patients." in: Pharmacogenetics and genomics, Vol. 20, Issue 10, pp. 634-7, 2010 (PubMed).

Hosts (68), (57), (5)
Reactivities (119), (31), (28), (14), (14), (13), (12), (2), (1), (1)
Applications (100), (35), (33), (30), (29), (22), (19), (17), (7), (6), (3), (3), (1)
Conjugates (4), (4), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2)
Epitopes (8), (8), (4), (3), (2), (2), (2), (1), (1)
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