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DCAF8 antibody (DDB1 and CUL4 Associated Factor 8) (AA 1-274)

Details for Product anti-DCAF8 Antibody No. ABIN394755, Supplier: Log in to see
Antigen
  • DCAF8
  • WDR42A
  • H326
  • MGC157366
  • wdr42a
  • AA408877
  • AA433120
  • AA792214
  • AU018973
  • C76055
  • D1Dau35e
  • D1Ucla4
  • Wdr42a
  • RGD1308513
  • DDB1 and CUL4 associated factor 8
  • WD repeat domain 42A
  • DCAF8
  • LOC100345000
  • TEgg075a15.1
  • Dcaf8
Epitope
AA 1-274
2
2
2
2
1
1
Reactivity
Human
10
2
2
2
2
2
1
1
Host
Mouse
7
3
Clonality (Clone)
Monoclonal ()
Application
Western Blotting (WB)
8
4
3
2
2
1
Options
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Immunogen WDR42A (AAH29399, 1 a.a. ~ 274 a.a) full length recombinant protein with GST tag. MW of the GST tag alone is 26 K
Clone 1A12
Isotype IgM kappa
Specificity WDR42A (AAH29399, 1 a.a. ~ 274 a.a) full length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Purification Purified
Alternative Name WDR42A (DCAF8 Antibody Abstract)
Background This gene encodes a WD repeat-containing protein that interacts with the Cul4-Ddb1 E3 ligase macromolecular complex. Multiple alternatively spliced transcript variants have been found for this gene.
Synonyms: DKFZp781G1096, H326, MGC99640 WD repeat domain 42A
Molecular Weight 66852 DA
Gene ID 50717
Research Area Cell Structure
Application Notes Western blot = 1:500-1000
Comment

Background: This gene encodes a WD repeat-containing protein that interacts with the Cul4-Ddb1 E3 ligase macromolecular complex. Multiple alternatively spliced transcript variants have been found for this gene.

Restrictions For Research Use only
Format Liquid
Buffer Phosphate buffered saline, pH 7.2
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles
Expiry Date 6 months
Supplier Images
Western Blotting (WB) image for anti-DCAF8 antibody (DDB1 and CUL4 Associated Factor 8) (AA 1-274) (ABIN394755) WDR42A monoclonal antibody (M01A), clone 1A12 Western Blot analysis of WDR42A express...
Background publications Venkatesan, Rual, Vazquez, Stelzl, Lemmens, Hirozane-Kishikawa, Hao, Zenkner, Xin, Goh, Yildirim, Simonis, Heinzmann, Gebreab, Sahalie, Cevik, Simon, de Smet, Dann, Smolyar, Vinayagam, Yu et al.: "An empirical framework for binary interactome mapping...." in: Nature methods, Vol. 6, Issue 1, pp. 83-90, 2008 (PubMed).

Angers, Li, Yi, MacCoss, Moon, Zheng: "Molecular architecture and assembly of the DDB1-CUL4A ubiquitin ligase machinery." in: Nature, Vol. 443, Issue 7111, pp. 590-3, 2006 (PubMed).

Jin, Arias, Chen, Harper, Walter: "A family of diverse Cul4-Ddb1-interacting proteins includes Cdt2, which is required for S phase destruction of the replication factor Cdt1." in: Molecular cell, Vol. 23, Issue 5, pp. 709-21, 2006 (PubMed).

Kimura, Wakamatsu, Suzuki, Ota, Nishikawa, Yamashita, Yamamoto, Sekine, Tsuritani, Wakaguri, Ishii, Sugiyama, Saito, Isono, Irie, Kushida, Yoneyama, Otsuka, Kanda, Yokoi, Kondo, Wagatsuma, Murakawa et al.: "Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. ..." in: Genome research, Vol. 16, Issue 1, pp. 55-65, 2006 (PubMed).

Rual, Venkatesan, Hao, Hirozane-Kishikawa, Dricot, Li, Berriz, Gibbons, Dreze, Ayivi-Guedehoussou, Klitgord, Simon, Boxem, Milstein, Rosenberg, Goldberg, Zhang, Wong, Franklin, Li, Albala, Lim et al.: "Towards a proteome-scale map of the human protein-protein interaction network. ..." in: Nature, Vol. 437, Issue 7062, pp. 1173-8, 2005 (PubMed).