DDB1 and CUL4 Associated Factor 8 (DCAF8) (AA 1-274) antibody

Details for Product No. ABIN394755
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Antigen
Synonyms DCAF8, WDR42A, H326, MGC157366, wdr42a, AA408877, AA433120, AA792214, AU018973, C76055, D1Dau35e, D1Ucla4, Wdr42a, RGD1308513
Epitope
AA 1-274
(2), (1), (1), (1)
Reactivity
Human
(5)
Host
Mouse
(3), (2)
Clonality (Clone)
Monoclonal ()
Application
Western Blotting (WB)
(4), (2), (2), (1)
Pubmed 5 references available
Quantity 200 µL
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Catalog No. ABIN394755
450.00 $
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Immunogen WDR42A (AAH29399, 1 a.a. ~ 274 a.a) full length recombinant protein with GST tag. MW of the GST tag alone is 26 K
Clone 1A12
Isotype IgM kappa
Specificity WDR42A (AAH29399, 1 a.a. ~ 274 a.a) full length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Purification Purified
Alternative Name WDR42A
Background This gene encodes a WD repeat-containing protein that interacts with the Cul4-Ddb1 E3 ligase macromolecular complex. Multiple alternatively spliced transcript variants have been found for this gene.
Synonyms: DKFZp781G1096, H326, MGC99640 WD repeat domain 42A
Molecular Weight 66852 DA
Gene ID 50717
Research Area Cell Structure
Application Notes Western blot = 1:500-1000
Comment

Background: This gene encodes a WD repeat-containing protein that interacts with the Cul4-Ddb1 E3 ligase macromolecular complex. Multiple alternatively spliced transcript variants have been found for this gene.

Restrictions For Research Use only
Format Liquid
Buffer Phosphate buffered saline, pH 7.2
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles
Expiry Date 6 months
Supplier Images
anti-DDB1 and CUL4 Associated Factor 8 (DCAF8) (AA 1-274) antibody WDR42A monoclonal antibody (M01A), clone 1A12 Western Blot analysis of WDR42A expression in A-549.
Background publications Rual, Venkatesan, Hao et al.: "Towards a proteome-scale map of the human protein-protein interaction network." in: Nature, Vol. 437, Issue 7062, pp. 1173-8, 2005 (PubMed).

Talmud, Drenos, Shah et al.: "Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes." in: Genome research, Vol. 16, Issue 1, pp. 55-65, 2006 (PubMed).

Jin, Arias, Chen et al.: "A family of diverse Cul4-Ddb1-interacting proteins includes Cdt2, which is required for S phase destruction of the replication factor Cdt1." in: Molecular cell, Vol. 23, Issue 5, pp. 709-21, 2006 (PubMed).

Angers, Li, Yi et al.: "Molecular architecture and assembly of the DDB1-CUL4A ubiquitin ligase machinery." in: Nature, Vol. 443, Issue 7111, pp. 590-3, 2006 (PubMed).

Venkatesan, Rual, Vazquez et al.: "An empirical framework for binary interactome mapping...." in: Nature methods, Vol. 6, Issue 1, pp. 83-90, 2008 (PubMed).

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