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Details for Product No. ABIN394755

DDB1 and CUL4 Associated Factor 8 (DCAF8) antibody

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Antigen
Synonyms H326, WDR42A, AA408877, AA433120, AA792214, AU018973, C76055, D1Dau35e, D1Ucla4, Wdr42a, RGD1308513, DCAF8, MGC157366, wdr42a
Reactivity
»Alternatives Human
Host
»Alternatives Mouse
Clonality (Clone) Monoclonal ()
Application
»Alternatives ELISA, Western Blotting (WB)
Pubmed 5 references available
Catalog no. ABIN394755
Quantity 200 µL
Price
450.00 $   Plus shipping costs $45.00
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Availability Will be delivered in 2 to 3 Business Days
Immunogen WDR42A (AAH29399, 1 a.a. ~ 274 a.a) full length recombinant protein with GST tag. MW of the GST tag alone is 26 K
Clone 1A12
Isotype IgM kappa
Specificity WDR42A (AAH29399, 1 a.a. ~ 274 a.a) full length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Purification Purified
Alternative Name WDR42A
Background This gene encodes a WD repeat-containing protein that interacts with the Cul4-Ddb1 E3 ligase macromolecular complex. Multiple alternatively spliced transcript variants have been found for this gene.
Synonyms: DKFZp781G1096, H326, MGC99640 WD repeat domain 42A
Molecular Weight 66852 DA
Gene ID 50717
Research Area Cell Structure
Application Notes ELISA ~~ 1ug/ml~3ng/ml Western blot ~~ 1:500~1000
Comment

Background: This gene encodes a WD repeat-containing protein that interacts with the Cul4-Ddb1 E3 ligase macromolecular complex. Multiple alternatively spliced transcript variants have been found for this gene.

Restrictions For Research Use only
Format Liquid
Buffer Phosphate buffered saline, pH 7.2
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles
Expiry Date 6 months
Background publications Rual, Venkatesan, Hao et al.: "Towards a proteome-scale map of the human protein-protein interaction network." in: Nature, Vol. 437, Issue 7062, pp. 1173-8, 2005 (PubMed).

Kimura, Wakamatsu, Suzuki et al.: "Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes." in: Genome research, Vol. 16, Issue 1, pp. 55-65, 2006 (PubMed).

Jin, Arias, Chen et al.: "A family of diverse Cul4-Ddb1-interacting proteins includes Cdt2, which is required for S phase destruction of the replication factor Cdt1." in: Molecular cell, Vol. 23, Issue 5, pp. 709-21, 2006 (PubMed).

Angers, Li, Yi et al.: "Molecular architecture and assembly of the DDB1-CUL4A ubiquitin ligase machinery." in: Nature, Vol. 443, Issue 7111, pp. 590-3, 2006 (PubMed).

Venkatesan, Rual, Vazquez et al.: "An empirical framework for binary interactome mapping." in: Nature methods, Vol. 6, Issue 1, pp. 83-90, 2008 (PubMed).

Alternatives for antigen "DDB1 and CUL4 Associated Factor 8 (DCAF8)", type "Antibodies"
Hosts (3), (3)
Reactivities (6)
Applications (6), (2), (2), (1)
Epitopes (2), (1)
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