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Details for Product No. ABIN394826

Potassium Inwardly-Rectifying Channel, Subfamily J, Member 15 (KCNJ15) antibody

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Antigen
Synonyms IRKK, KIR1.3, KIR4.2, Kir4.2, AI182284, AI267127, 4930414N08Rik, kcnj1, MGC68935, KCNJ15
Reactivity
»Alternatives Human
Host
»Alternatives Mouse
Clonality (Clone) Monoclonal ()
Application
»Alternatives ELISA, Western Blotting (WB)
Pubmed 5 references available
Catalog no. ABIN394826
Quantity 0.1 mg
Price
450.00 $   Plus shipping costs $45.00
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Availability Will be delivered in 2 to 3 Business Days
Immunogen KCNJ15 (NP_002234, 290 a.a. ~ 356 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 K
Clone 1B2
Isotype IgG2a kappa
Specificity KCNJ15 (NP_002234, 290 a.a. ~ 356 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Purification This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
Alternative Name KCNJ15
Background Synonyms: Serine protease inhibitor J6, 47 kDa heat shock protein, Collagen-binding protein, Colligin, Serpin H1,Hsp47, Cbp1, Serpinh1
Molecular Weight 42577 DA
Gene ID 12406
UniProt NP_002234
Research Area Cell Structure
Application Notes ELISA ~~ 1ug/ml~3ng/ml Western blot ~~ 1:500~1000
Comment

Background: Potassium channels are present in most mammalian cells, where they participate in a wide range of physiologic responses. The protein encoded by this gene is an integral membrane protein and inward-rectifier type potassium channel. The encoded protein has a greater tendency to allow potassium to flow into a cell rather than out of a cell. Three transcript variants encoding the same protein have been found for this gene.

Restrictions For Research Use only
Buffer PBS with 0.09% (w/v) sodium azide.
Preservative Sodium azide
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles
Expiry Date 6 months
Background publications Huang, Sindic, Hill et al.: "Interaction of the Ca2+-sensing receptor with the inwardly rectifying potassium channels Kir4.1 and Kir4.2 results in inhibition of channel function." in: American journal of physiology. Renal physiology, Vol. 292, Issue 3, pp. F1073-81, 2007 (PubMed).

Barbe, Lundberg, Oksvold et al.: "Toward a confocal subcellular atlas of the human proteome." in: Molecular & cellular proteomics : MCP, Vol. 7, Issue 3, pp. 499-508, 2008 (PubMed).

Ji, Foo, ORoak et al.: "Rare independent mutations in renal salt handling genes contribute to blood pressure variation." in: Nature genetics, Vol. 40, Issue 5, pp. 592-9, 2008 (PubMed).

Sindic, Huang, Chen et al.: "MUPP1 complexes renal K+ channels to alter cell surface expression and whole cell currents." in: American journal of physiology. Renal physiology, Vol. 297, Issue 1, pp. F36-45, 2009 (PubMed).

Okamoto, Iwasaki, Nishimura et al.: "Identification of KCNJ15 as a susceptibility gene in Asian patients with type 2 diabetes mellitus." in: American journal of human genetics, Vol. 86, Issue 1, pp. 54-64, 2010 (PubMed).

Alternatives for antigen "Potassium Inwardly-Rectifying Channel, Subfamily J, Member 15 (KCNJ15)", type "Antibodies"
Hosts (7), (3)
Reactivities (10), (2), (2)
Applications (9), (5), (2), (1), (1), (1)
Epitopes (3), (2), (2), (1), (1)
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