You are viewing an incomplete version of our website. Please click to reload the website as full version.

BCAS1 antibody (Breast Carcinoma Amplified Sequence 1) (AA 1-81)

Details for Product anti-BCAS1 Antibody No. ABIN394844, Supplier: Log in to see
Antigen
  • 2210416M21Rik
  • 9030223A09Rik
  • AI841227
  • AIBC1
  • Band83
  • BCAS1
  • MGC152145
  • NABC1
  • Pmes-2
Epitope
AA 1-81
18
18
15
4
4
1
1
1
Reactivity
Human
72
16
14
1
1
1
1
Host
Mouse
63
9
Clonality (Clone)
Monoclonal ()
Conjugate
This BCAS1 antibody is un-conjugated
3
3
3
2
2
2
2
1
1
1
1
1
1
1
1
Application
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), ELISA, Western Blotting (WB)
56
32
17
16
12
4
3
1
1
Supplier
Log in to see
Supplier Product No.
Log in to see
Request

Get this product for free

It's quick and easy to submit your validation proposal. I want to validate this product

Learn more

Available images

Immunogen BCAS1 (NP_003648, 1 a.a. ~ 81 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 K
Clone 1B5
Isotype IgG2a kappa
Specificity BCAS1 (NP_003648, 1 a.a. ~ 81 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Purification This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
Alternative Name BCAS1 (BCAS1 Antibody Abstract)
Background Synonyms: Serine protease inhibitor J6, 47 kDa heat shock protein, Collagen-binding protein, Colligin, Serpin H1,Hsp47, Cbp1, Serpinh1
Molecular Weight 61709 DA
Gene ID 12406
NCBI Accession NP_003648
Research Area Cancer, Cell Structure
Application Notes ELISA ~~ 1ug/ml~3ng/ml Western blot ~~ 1:500~1000 Immunohistochemistry ~~ 1.5ug/ml
Comment

Background: This gene resides in a region at 20q13 which is amplified in a variety of tumor types and associated with more aggressive tumor phenotypes. Among the genes identified from this region, it was found to be highly expressed in three amplified breast cancer cell lines and in one breast tumor without amplification at 20q13.2. However, this gene is not in the common region of maximal amplification and its expression was not detected in the breast cancer cell line MCF7, in which this region is highly amplified. Although not consistently expressed, this gene is a candidate oncogene.

Restrictions For Research Use only
Concentration 0.5 mg/ml
Buffer PBS with 0.09% (w/v) sodium azide.
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles
Expiry Date 6 months
Supplier Images
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) image for anti-BCAS1 antibody (Breast Carcinoma Amplified Sequence 1) (AA 1-81) (ABIN394844) Immunoperoxidase of monoclonal antibody to BCAS1 on formalin-fixed paraffin-embedded ...
Background publications Rose, Behm, Drgon, Johnson, Uhl: "Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score." in: Molecular medicine (Cambridge, Mass.), Vol. 16, Issue 7-8, pp. 247-53, 2010 (PubMed).

Ewing, Chu, Elisma, Li, Taylor, Climie, McBroom-Cerajewski, Robinson, OConnor, Li, Taylor, Dharsee, Ho, Heilbut, Moore, Zhang, Ornatsky, Bukhman, Ethier, Sheng, Vasilescu, Abu-Farha, Lambert, Duewel et al.: "Large-scale mapping of human protein-protein interactions by mass spectrometry. ..." in: Molecular systems biology, Vol. 3, pp. 89, 2007 (PubMed).

Burmester, Suarez, Lin, Jin, Miller, Zhang, Salzman, Reding, Catalona: "Analysis of candidate genes for prostate cancer." in: Human heredity, Vol. 57, Issue 4, pp. 172-8, 2004 (PubMed).

Gerhard, Wagner, Feingold, Shenmen, Grouse, Schuler, Klein, Old, Rasooly, Good, Guyer, Peck, Derge, Lipman, Collins, Jang, Sherry, Feolo, Misquitta, Lee, Rotmistrovsky, Greenhut, Schaefer, Buetow et al.: "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). ..." in: Genome research, Vol. 14, Issue 10B, pp. 2121-7, 2004 (PubMed).

Beardsley, Kowbel, Lataxes, Mannino, Xin, Kim, Collins, Brown: "Characterization of the novel amplified in breast cancer-1 (NABC1) gene product." in: Experimental cell research, Vol. 290, Issue 2, pp. 402-13, 2003 (PubMed).