|+1 404 474 4654|
|+1 888 205 9894 (TF)|
Breast Carcinoma Amplified Sequence 1 (BCAS1) antibody
|Synonyms||AIBC1, NABC1, AI841227, 2210416M21Rik, 9030223A09Rik, Band83, Pmes-2, BCAS1, MGC152145|
Alternatives ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
|5 references available|
|Quantity||0.1mg (0.5 mg/ml)|
|Price||450.00 $ Plus shipping costs $45.00|
|Availability||Will be delivered in 2 to 3 Business Days|
|Immunogen||BCAS1 (NP_003648, 1 a.a. ~ 81 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 K|
|Description||Other names: AIBC1, NABC1breast carcinoma amplified sequence 1|
|Characteristics||Purified Mouse Monoclonal Antibody (Mab)|
|Specificity||BCAS1 (NP_003648, 1 a.a. ~ 81 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.|
|Molecular Weight||61709 DA|
Background: This gene resides in a region at 20q13 which is amplified in a variety of tumor types and associated with more aggressive tumor phenotypes. Among the genes identified from this region, it was found to be highly expressed in three amplified breast cancer cell lines and in one breast tumor without amplification at 20q13.2. However, this gene is not in the common region of maximal amplification and its expression was not detected in the breast cancer cell line MCF7, in which this region is highly amplified. Although not consistently expressed, this gene is a candidate oncogene.
|Application Notes||ELISA ~~ 1ug/ml~3ng/ml Western blot ~~ 1:500~1000 Immunohistochemistry ~~ 1.5ug/ml|
|Buffer||Clear, colorless solution in phosphate buffered saline, pH 7.2 .|
|Storage||Maintain refrigerated at 2-8 deg C for up to 6 months. For long term storage store at -20 deg C in small aliquots to prevent freeze-thaw cycles|
|Research Area||Cancer, Cell Structure|
|Restrictions||For Research Use only|
|Immunoperoxidase of monoclonal antibody to BCAS1 ( Cat# AT1279a ) on formalin-fixed paraffin-embedded human small Intestine. [antibody concentration 1.5 ug/ml]|
Beardsley, Kowbel, Lataxes et al.: "Characterization of the novel amplified in breast cancer-1 (NABC1) gene product." in: Experimental cell research, Vol. 290, Issue 2, pp. 402-13, 2003 (PubMed).
Gerhard, Wagner, Feingold et al.: "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)." in: Genome research, Vol. 14, Issue 10B, pp. 2121-7, 2004 (PubMed).
Burmester, Suarez, Lin et al.: "Analysis of candidate genes for prostate cancer." in: Human heredity, Vol. 57, Issue 4, pp. 172-8, 2004 (PubMed).
Ewing, Chu, Elisma et al.: "Large-scale mapping of human protein-protein interactions by mass spectrometry." in: Molecular systems biology, Vol. 3, pp. 89, 2007 (PubMed).
Rose, Behm, Drgon et al.: "Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score." in: Molecular medicine (Cambridge, Mass.), Vol. 16, Issue 7-8, pp. 247-53, 2010 (PubMed).
|Hosts||Rabbit (28), Mouse (2)|
|Reactivities||Human (30), Mouse (Murine) (18), Rat (Rattus) (18)|
|Applications||Immunofluorescence (IF) (16), Western Blotting (WB) (15), ELISA (9), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (8), Immunohistochemistry (Formalin-fixed Sections) (IHC (f)) (3), Immunocytochemistry (ICC) (1), Immunoelectron Microscopy (IEM) (1), Immunohistochemistry (IHC) (1)|
|Conjugates||Alexa Fluor 350 (1), Alexa Fluor 488 (1), Alexa Fluor 555 (1), Alexa Fluor 647 (1), Biotin (1), Cy3 (1), Cy5 (1), Cy5.5 (1), Cy7 (1), FITC (1), Gold (1), HRP (1), PE (1), PE-Cy3 (1), PE-Cy5 (1), PE-Cy5.5 (1), PE-Cy7 (1), Un-conjugated (1)|
|Epitopes||AA 542-584 (18), C-Term (3), AA 532-550 (2)|