Adaptor-Related Protein Complex 4, beta 1 Subunit (AP4B1) (AA 640-740) antibody

Details for Product No. ABIN394856
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Synonyms AP4B1, DDBDRAFT_0185456, DDBDRAFT_0234245, DDB_0185456, DDB_0234245, BETA-4, CPSQ5, SPG47, 1810038H16Rik, AV004952, Ap4b4
AA 640-740
(15), (13), (5), (3), (2), (2), (1), (1), (1)
(27), (1), (1)
(21), (6)
Clonality (Clone)
Monoclonal ()
(2), (2), (2), (2), (2), (2)
ELISA, Western Blotting (WB)
(23), (18), (3)
Pubmed 5 references available
Quantity 0.1 mg
Shipping to United States ( )
Availability Will be delivered in 8 to 11 Business Days
Immunogen AP4B1 (NP_006585, 640 a.a. ~ 740 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 K
Clone 1B7
Isotype IgG1 kappa
Specificity AP4B1 (NP_006585, 640 a.a. ~ 740 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Purification This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
Alternative Name AP4B1 (AP4B1 Antibody Abstract)
Background Synonyms: Serine protease inhibitor J6, 47 kDa heat shock protein, Collagen-binding protein, Colligin, Serpin H1,Hsp47, Cbp1, Serpinh1
Molecular Weight 83260 DA
Gene ID 12406
NCBI Accession NP_006585
Research Area Cell Structure
Application Notes ELISA ~~ 1ug/ml~3ng/ml Western blot ~~ 1:500~1000

Background: The heterotetrameric adaptor protein (AP) complexes sort integral membrane proteins at various stages of the endocytic and secretory pathways. AP4 is composed of 2 large chains, beta-4 (AP4B1) and epsilon-4 (AP4E1, MIM 607244), a medium chain, mu-4 (AP4M1, MIM 602296), and a small chain, sigma-4 (AP4S1, MIM 607243).

Restrictions For Research Use only
Buffer PBS with 0.09% (w/v) sodium azide.
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles
Expiry Date 6 months
Supplier Images
ELISA image for anti-Adaptor-Related Protein Complex 4, beta 1 Subunit (AP4B1) (AA 640-740) antibody (ABIN394856) Detection limit for recombinant GST tagged AP4B1 is approximately 0.3 ng/mL as a capt...
Background publications Ewing, Chu, Elisma et al.: "Large-scale mapping of human protein-protein interactions by mass spectrometry. ..." in: , Vol. 3, pp. 89, 2007 (PubMed).

Gregory, Barlow, McLay et al.: "The DNA sequence and biological annotation of human chromosome 1. ..." in: Nature, Vol. 441, Issue 7091, pp. 315-21, 2006 (PubMed).

Gerhard, Wagner, Feingold et al.: "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). ..." in: Genome research, Vol. 14, Issue 10B, pp. 2121-7, 2004 (PubMed).

Ota, Suzuki, Nishikawa et al.: "Complete sequencing and characterization of 21,243 full-length human cDNAs. ..." in: Nature genetics, Vol. 36, Issue 1, pp. 40-5, 2003 (PubMed).

Strausberg, Feingold, Grouse et al.: "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. ..." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 99, Issue 26, pp. 16899-903, 2002 (PubMed).

Catalog No. ABIN394856
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