Apoptosis Inhibitor 5 (API5) (AA 400-504) antibody

Details for Product No. ABIN394905
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Antigen
Synonyms api5l1, sr:nyz021, zgc:66211, wu:fb26c03, api5, API-5A, api5-A, MGC83290, API5, AAC-11, AAC11, AI196452
Epitope
AA 400-504
(14), (7), (7), (1), (1), (1), (1)
Reactivity
Human
(50), (26), (19), (12), (12), (12), (12)
Host
Mouse
(42), (8)
Clonality (Clone)
Monoclonal ()
Conjugate
Un-conjugated
(3), (3), (3), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application
Immunofluorescence (IF), Western Blotting (WB)
(36), (23), (14), (13), (10), (7), (6), (4)
Pubmed 5 references available
Quantity 0.1 mg
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Catalog No. ABIN394905
450.00 $
Plus shipping costs $45.00

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Immunogen API5 (AAH17709, 400 a.a. ~ 504 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 K
Clone 1C2
Isotype IgG2b kappa
Specificity API5 (AAH17709, 400 a.a. ~ 504 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Purification This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
Alternative Name API5
Background Synonyms: Serine protease inhibitor J6, 47 kDa heat shock protein, Collagen-binding protein, Colligin, Serpin H1,Hsp47, Cbp1, Serpinh1
Molecular Weight 57561 DA
Gene ID 12406
Research Area Cell Structure
Application Notes Western blot = 1:500-1000
Restrictions For Research Use only
Buffer PBS with 0.09% (w/v) sodium azide.
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles
Expiry Date 6 months
Supplier Images
anti-Apoptosis Inhibitor 5 (API5) (AA 400-504) antibody Immunofluorescence of monoclonal antibody to API5 on HeLa cell (antibody concentration 10 µg/mL). API5 monoclonal antibody (M01), clone 1C2 Western Blot analysis of API5 expression in Hela NE.
anti-Apoptosis Inhibitor 5 (API5) (AA 400-504) antibody (2) anti-Apoptosis Inhibitor 5 (API5) (AA 400-504) antibody (Image 2)
Background publications Morris, Michaud, Ji et al.: "Functional identification of Api5 as a suppressor of E2F-dependent apoptosis in vivo." in: PLoS genetics, Vol. 2, Issue 11, pp. e196, 2006 (PubMed).

Wang, Lee, Ma et al.: "Profiling microRNA expression in hepatocellular carcinoma reveals microRNA-224 up-regulation and apoptosis inhibitor-5 as a microRNA-224-specific target." in: The Journal of biological chemistry, Vol. 283, Issue 19, pp. 13205-15, 2008 (PubMed).

Rigou, Piddubnyak, Faye et al.: "The antiapoptotic protein AAC-11 interacts with and regulates Acinus-mediated DNA fragmentation." in: The EMBO journal, Vol. 28, Issue 11, pp. 1576-88, 2009 (PubMed).

Need, Attix, McEvoy et al.: "A genome-wide study of common SNPs and CNVs in cognitive performance in the CANTAB." in: Human molecular genetics, Vol. 18, Issue 23, pp. 4650-61, 2009 (PubMed).

Ren, Zhang, Shi et al.: "Pim-2 activates API-5 to inhibit the apoptosis of hepatocellular carcinoma cells through NF-kappaB pathway." in: Pathology oncology research : POR, Vol. 16, Issue 2, pp. 229-37, 2010 (PubMed).

Validation Images
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