Search, Find and Buy Antibodies, ELISA Kits and Proteins.
Loading Loading
Order hotline:
phone +1 404 474 4654
fax +1 888 205 9894 (TF)
Details for Product No. ABIN394905

Apoptosis Inhibitor 5 (API5) antibody

Request
Want additional data for this product?

The Independent Validation Initiative strives to provide you with high quality data. Find out more

Antigen
Synonyms AAC11, AAC-11, AI196452, api5l1, sr:nyz021, zgc:66211, wu:fb26c03, api5, API-5A, api5-A, MGC83290, API5
Reactivity
»Alternatives Human
Host
»Alternatives Mouse
Clonality (Clone) Monoclonal ()
Conjugate
»Alternatives Un-conjugated
Application
»Alternatives ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
Pubmed 5 references available
Catalog no. ABIN394905
Quantity 0.1 mg
Price
450.00 $   Plus shipping costs $45.00
Shipping to
Availability Will be delivered in 2 to 3 Business Days
Immunogen API5 (AAH17709, 400 a.a. ~ 504 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 K
Clone 1C2
Isotype IgG2b kappa
Specificity API5 (AAH17709, 400 a.a. ~ 504 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Purification This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
Alternative Name API5
Background Synonyms: Serine protease inhibitor J6, 47 kDa heat shock protein, Collagen-binding protein, Colligin, Serpin H1,Hsp47, Cbp1, Serpinh1
Molecular Weight 57561 DA
Gene ID 12406
Research Area Cell Structure
Application Notes ELISA ~~ 1ug/ml~3ng/ml Western blot ~~ 1:500~1000 Immunohistochemistry ~~ 1.5ug/ml Immunofluorescence
Restrictions For Research Use only
Buffer PBS with 0.09% (w/v) sodium azide.
Preservative Sodium azide
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles
Expiry Date 6 months
Background publications Morris, Michaud, Ji et al.: "Functional identification of Api5 as a suppressor of E2F-dependent apoptosis in vivo." in: PLoS genetics, Vol. 2, Issue 11, pp. e196, 2006 (PubMed).

Wang, Lee, Ma et al.: "Profiling microRNA expression in hepatocellular carcinoma reveals microRNA-224 up-regulation and apoptosis inhibitor-5 as a microRNA-224-specific target." in: The Journal of biological chemistry, Vol. 283, Issue 19, pp. 13205-15, 2008 (PubMed).

Rigou, Piddubnyak, Faye et al.: "The antiapoptotic protein AAC-11 interacts with and regulates Acinus-mediated DNA fragmentation." in: The EMBO journal, Vol. 28, Issue 11, pp. 1576-88, 2009 (PubMed).

Need, Attix, McEvoy et al.: "A genome-wide study of common SNPs and CNVs in cognitive performance in the CANTAB." in: Human molecular genetics, Vol. 18, Issue 23, pp. 4650-61, 2009 (PubMed).

Ren, Zhang, Shi et al.: "Pim-2 activates API-5 to inhibit the apoptosis of hepatocellular carcinoma cells through NF-kappaB pathway." in: Pathology oncology research : POR, Vol. 16, Issue 2, pp. 229-37, 2010 (PubMed).

Alternatives for antigen "Apoptosis Inhibitor 5 (API5)", type "Antibodies"
Hosts (31), (2)
Reactivities (33), (23), (17), (12), (12), (12), (12)
Applications (19), (12), (10), (10), (6), (5), (2)
Conjugates (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Epitopes (9), (2), (1), (1), (1)
Beacon