CGG Triplet Repeat Binding Protein 1 (CGGBP1) antibody

Antigen: CGG Triplet Repeat Binding Protein 1 (CGGBP1)

Synonyms: CGGBP, p20-CGGBP, AA960172, AL023996, AW045841, CGGBP1

Clonality: Monoclonal (1D11)

Host: Mouse

Reactivity: Human

Application: ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)

Certificates: ISO 9001:2008

Catalog no.: ABIN394975

Additional Information

Alternative name: CGGBP1

Gene ID: 8545

UniProt: NP_003654

Immunogen: CGGBP1 (NP_003654, 58 a.a. ~ 168 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 K

Isotype: IgG1 kappa

Clone: 1D11

Description: Other names: CGGBP, p20CGGBP CGG triplet repeat binding protein 1

Characteristics: Purified Mouse Monoclonal Antibody (Mab)

Specificity: CGGBP1 (NP_003654, 58 a.a. ~ 168 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Molecular Weight: 18820 DA

Comments:

Background: CGGBP1 influences expression of the FMR1 gene (MIM 309550), which is associated with the fragile X mental retardation syndrome (MIM 300624), by specifically interacting with the 5-prime (CGG)n-3-prime repeat in its 5-prime UTR.

Application Details

Application Notes: ELISA ~~ 1ug/ml~3ng/ml Western blot ~~ 1:500~1000 Immunohistochemistry ~~ 1.5ug/ml Immunofluorescence

Purification: Purified

Buffer: Clear, colorless solution in phosphate buffered saline, pH 7.2 .

Storage: Maintain refrigerated at 2-8 deg C for up to 6 months. For long term storage store at -20 deg C in small aliquots to prevent freeze-thaw cycles

Research Area: Cell Structure

Restrictions: For Research Use only

Images

Immunofluorescence of to CGGBP1 ( Cat# AT1509a ) on HeLa cell . CGGBP1 monoclonal antibody (M02), clone 1D11 Western Blot analysis of CGGBP1 expression in K-562 ( Cat # L009V1 ).

anti-CGG Triplet Repeat Binding Protein 1 (CGGBP1) antibody (Image 2)

Publications

Product: Wiemann, Arlt, Huber et al.: "From ORFeome to biology: a functional genomics pipeline." in: Genome research, Vol. 14, Issue 10B, pp. 2136-44, 2004 (PubMed).

Stelzl, Worm, Lalowski et al.: "A human protein-protein interaction network: a resource for annotating the proteome." in: Cell, Vol. 122, Issue 6, pp. 957-68, 2005 (PubMed).

Mehrle, Rosenfelder, Schupp et al.: "The LIFEdb database in 2006." in: Nucleic acids research, Vol. 34, Issue Database issue, pp. D415-8, 2005 (PubMed).

Arrieta, Télez, Huerta et al.: "Fragile X gene stability in Basque Valleys: prevalence of premutation and intermediate alleles." in: Human biology, Vol. 80, Issue 6, pp. 593-600, 2009 (PubMed).

Gulyĭ, Orlov, Dizhe et al.: "[The role of ZF5 and CGGBP-20 transcription factors in expression regulation of human FMR1 gene responsible for X-fragile syndrome]." in: Tsitologiia, Vol. 51, Issue 12, pp. 1005-12, 2010 (PubMed).