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RAB21, Member RAS Oncogene Family (RAB21) (AA 116-226) antibody

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Synonyms MGC68816, RAB21, 9630024B22
AA 116-226
(21), (15), (3), (3), (2), (2), (1), (1)
(65), (23), (23), (4), (4)
(39), (26)
Clonality (Clone)
Monoclonal ()
(3), (3), (3), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Immunofluorescence (IF), Western Blotting (WB)
(51), (24), (24), (16), (15), (11), (1)
Pubmed 5 references available
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Quantity 0.1 mg
Shipping to United States ( )
Availability Will be delivered in 8 to 11 Business Days
Immunogen RAB21 (NP_055814, 116 a.a. ~ 226 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 K
Clone 1F6
Isotype IgG1 kappa
Specificity RAB21 (NP_055814, 116 a.a. ~ 226 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Purification This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
Alternative Name RAB21 (RAB21 Antibody Abstract)
Background Synonyms: Serine protease inhibitor J6, 47 kDa heat shock protein, Collagen-binding protein, Colligin, Serpin H1,Hsp47, Cbp1, Serpinh1
Molecular Weight 24348 DA
Gene ID 12406
NCBI Accession NP_055814
Research Area Cell Structure
Application Notes Western blot = 1:500-1000

Background: RAB21 belongs to the RAB family of small GTP-binding proteins that regulate intracellular vesicle targeting (Opdam et al., 2000 [PubMed 10887961]).

Restrictions For Research Use only
Buffer PBS with 0.09% (w/v) sodium azide.
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles
Expiry Date 6 months
Supplier Images
Western Blotting (WB) image for anti-RAB21, Member RAS Oncogene Family (RAB21) (AA 116-226) antibody (ABIN395106) Immunofluorescence of monoclonal antibody to RAB21 on HeLa cell (antibody concentrati...
Immunohistochemistry (IHC) image for anti-RAB21, Member RAS Oncogene Family (RAB21) (AA 116-226) antibody (ABIN395106) anti-RAB21, Member RAS Oncogene Family (RAB21) (AA 116-226) antibody (Image 2)
Background publications Burgo, Sotirakis, Simmler et al.: "Role of Varp, a Rab21 exchange factor and TI-VAMP/VAMP7 partner, in neurite growth." in: EMBO reports, Vol. 10, Issue 10, pp. 1117-24, 2009 (PubMed).

Pellinen, Tuomi, Arjonen et al.: "Integrin trafficking regulated by Rab21 is necessary for cytokinesis." in: Developmental cell, Vol. 15, Issue 3, pp. 371-85, 2008 (PubMed).

Delprato, Lambright: "Structural basis for Rab GTPase activation by VPS9 domain exchange factors." in: Nature structural & molecular biology, Vol. 14, Issue 5, pp. 406-12, 2007 (PubMed).

Pellinen, Arjonen, Vuoriluoto et al.: "Small GTPase Rab21 regulates cell adhesion and controls endosomal traffic of beta1-integrins." in: The Journal of cell biology, Vol. 173, Issue 5, pp. 767-80, 2006 (PubMed).

Mehrle, Rosenfelder, Schupp et al.: "The LIFEdb database in 2006." in: Nucleic acids research, Vol. 34, Issue Database issue, pp. D415-8, 2005 (PubMed).

Catalog No. ABIN395106
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