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Details for Product No. ABIN395106

RAB21, Member RAS Oncogene Family (RAB21) antibody

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Synonyms 9630024B22, MGC68816, RAB21
»Alternatives Human
»Alternatives Mouse
Clonality (Clone) Monoclonal ()
»Alternatives Un-conjugated
»Alternatives ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
Pubmed 5 references available
Catalog no. ABIN395106
Quantity 0.1 mg
450.00 $   Plus shipping costs $45.00
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Availability Will be delivered in 2 to 3 Business Days
Immunogen RAB21 (NP_055814, 116 a.a. ~ 226 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 K
Clone 1F6
Isotype IgG1 kappa
Specificity RAB21 (NP_055814, 116 a.a. ~ 226 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Purification This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
Alternative Name RAB21
Background Synonyms: Serine protease inhibitor J6, 47 kDa heat shock protein, Collagen-binding protein, Colligin, Serpin H1,Hsp47, Cbp1, Serpinh1
Molecular Weight 24348 DA
Gene ID 12406
UniProt NP_055814
Research Area Cell Structure
Application Notes ELISA ~~ 1ug/ml~3ng/ml Western blot ~~ 1:500~1000 Immunohistochemistry ~~ 1.5ug/ml Immunofluorescence

Background: RAB21 belongs to the RAB family of small GTP-binding proteins that regulate intracellular vesicle targeting (Opdam et al., 2000 [PubMed 10887961]).

Restrictions For Research Use only
Buffer PBS with 0.09% (w/v) sodium azide.
Preservative Sodium azide
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles
Expiry Date 6 months
Background publications Mehrle, Rosenfelder, Schupp et al.: "The LIFEdb database in 2006." in: Nucleic acids research, Vol. 34, Issue Database issue, pp. D415-8, 2005 (PubMed).

Pellinen, Arjonen, Vuoriluoto et al.: "Small GTPase Rab21 regulates cell adhesion and controls endosomal traffic of beta1-integrins." in: The Journal of cell biology, Vol. 173, Issue 5, pp. 767-80, 2006 (PubMed).

Delprato, Lambright: "Structural basis for Rab GTPase activation by VPS9 domain exchange factors." in: Nature structural & molecular biology, Vol. 14, Issue 5, pp. 406-12, 2007 (PubMed).

Pellinen, Tuomi, Arjonen et al.: "Integrin trafficking regulated by Rab21 is necessary for cytokinesis." in: Developmental cell, Vol. 15, Issue 3, pp. 371-85, 2008 (PubMed).

Burgo, Sotirakis, Simmler et al.: "Role of Varp, a Rab21 exchange factor and TI-VAMP/VAMP7 partner, in neurite growth." in: EMBO reports, Vol. 10, Issue 10, pp. 1117-24, 2009 (PubMed).

Alternatives for antigen "RAB21, Member RAS Oncogene Family (RAB21)", type "Antibodies"
Hosts (23), (13)
Reactivities (36), (17), (17), (12), (12)
Applications (27), (13), (12), (10), (7), (3), (1)
Conjugates (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Epitopes (11), (3), (2), (1)