TACR1 antibody (Tachykinin Receptor 1) (Met10)

Details for Product anti-TACR1 Antibody No. ABIN395116, Supplier: Log in to see
Antigen
  • NK1R
  • NKIR
  • SPR
  • TAC1R
  • Nk1r
  • Spr
  • Tac1r
  • nk1R
  • Tacr1
  • ASPR
  • substance-P receptor-like
  • tachykinin receptor 1
  • LOC100053491
  • TACR1
  • Tacr1
Alternatives
anti-Human TACR1 antibody for Immunohistochemistry (Paraffin-embedded Sections)
Epitope
Met10
22
19
18
15
11
11
4
3
3
3
3
3
2
2
1
1
1
1
1
1
1
1
1
1
Reactivity
Human
146
71
62
12
10
6
5
5
4
4
2
2
1
1
1
1
Host
Mouse
136
15
7
Clonality (Clone)
Monoclonal ()
Conjugate
This TACR1 antibody is un-conjugated
9
9
7
4
3
3
3
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Application
ELISA
97
53
46
33
25
25
17
13
7
2
1
1
Options
Supplier
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Supplier Product No.
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Immunogen TACR1 (NP_001049, 140 a.a. ~ 244 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 K
Clone 1F7
Isotype IgG2a kappa
Specificity TACR1 (NP_001049, 140 a.a. ~ 244 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Purification This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
Alternative Name TACR1 (TACR1 Antibody Abstract)
Background Synonyms: Serine protease inhibitor J6, 47 kDa heat shock protein, Collagen-binding protein, Colligin, Serpin H1,Hsp47, Cbp1, Serpinh1
Molecular Weight 46251 DA
Gene ID 12406
NCBI Accession NP_001049
Research Area Cell Structure, Metabolism
Pathways Regulation of Systemic Arterial Blood Pressure by Hormones, Feeding Behaviour, Smooth Muscle Cell Migration
Application Notes ELISA ~~ 1ug/ml~3ng/ml
Comment

Background: This gene belongs to a gene family of tachykinin receptors. These tachykinin receptors are characterized by interactions with G proteins and contain seven hydrophobic transmembrane regions. This gene encodes the receptor for the tachykinin substance P, also referred to as neurokinin 1. The encoded protein is also involved in the mediation of phosphatidylinositol metabolism of substance P.

Restrictions For Research Use only
Buffer PBS with 0.09% (w/v) sodium azide.
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles
Expiry Date 6 months
Supplier Images
ELISA image for anti-Tachykinin Receptor 1 (TACR1) (Met10) antibody (ABIN395116) Detection limit for recombinant GST tagged TACR1 is approximately 0.1 ng/mL as a capt...
Background publications Pinheiro, Bulik, Thornton, Sullivan, Root, Bloss, Berrettini, Schork, Kaye, Bergen, Magistretti, Brandt, Crawford, Crow, Fichter, Goldman, Halmi, Johnson, Kaplan, Keel, Klump, La Via, Mitchell, Strober, Rotondo, Treasure, Woodside: "Association study of 182 candidate genes in anorexia nervosa." in: American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics, Vol. 153B, Issue 5, pp. 1070-80, 2010 (PubMed).

Saus, Brunet, Armengol, Alonso, Crespo, Fernández-Aranda, Guitart, Martín-Santos, Menchón, Navinés, Soria, Torrens, Urretavizcaya, Vallès, Gratacòs, Estivill: "Comprehensive copy number variant (CNV) analysis of neuronal pathways genes in psychiatric disorders identifies rare variants within patients." in: Journal of psychiatric research, Vol. 44, Issue 14, pp. 971-8, 2010 (PubMed).

Rose, Behm, Drgon, Johnson, Uhl: "Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score." in: Molecular medicine (Cambridge, Mass.), Vol. 16, Issue 7-8, pp. 247-53, 2010 (PubMed).

Davila, Froeling, Tan, Bonnard, Boland, Snippe, Hibberd, Seielstad: "New genetic associations detected in a host response study to hepatitis B vaccine." in: Genes and immunity, Vol. 11, Issue 3, pp. 232-8, 2010 (PubMed).

Herlyn, Müller-Hilke, Wendt, Hecker, Mittlmeier, Gradl: "Frequencies of polymorphisms in cytokines, neurotransmitters and adrenergic receptors in patients with complex regional pain syndrome type I after distal radial fracture." in: The Clinical journal of pain, Vol. 26, Issue 3, pp. 175-81, 2010 (PubMed).

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