You are viewing an incomplete version of our website. Please click to reload the website as full version.

WD Repeat Domain 4 (WDR4) (AA 1-267) antibody

Details for Product No. ABIN395139, Supplier: Log in to see
Antigen
  • TRM82
  • TRMT82
  • AI415180
  • AI448349
  • D530049K22Rik
Epitope
AA 1-267
15
13
10
5
4
4
3
3
2
1
1
Reactivity
Human
45
5
5
2
1
1
Host
Mouse
37
6
2
Clonality (Clone)
Monoclonal ()
Conjugate
Un-conjugated
2
2
2
2
2
2
Application
Western Blotting (WB)
39
23
5
4
3
2
2
Supplier
Log in to see
Supplier Product No.
Log in to see
Request

Showcase your results, aid the scientific community, and receive a full refund.

Contribute a validation

Learn more

Available images

Immunogen WDR4 (AAH01074, 1 a.a. ~ 267 a.a) full length recombinant protein with GST tag. MW of the GST tag alone is 26 K
Clone 1F9
Isotype IgG1 kappa
Specificity WDR4 (AAH01074, 1 a.a. ~ 267 a.a) full length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Purification This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
Alternative Name WDR4 (WDR4 Antibody Abstract)
Background Synonyms: Serine protease inhibitor J6, 47 kDa heat shock protein, Collagen-binding protein, Colligin, Serpin H1,Hsp47, Cbp1, Serpinh1
Molecular Weight 45490 DA
Gene ID 12406
Research Area Cell Signaling, Cell Structure
Application Notes Western blot = 1:500-1000
Comment

Background: This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. This gene is excluded as a candidate for a form of nonsyndromic deafness (DFNB10), but is still a candidate for other disorders mapped to 21q22.3 as well as for the development of Down syndrome phenotypes. Two transcript variants encoding the same protein have been found for this gene.

Restrictions For Research Use only
Buffer PBS with 0.09% (w/v) sodium azide.
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles
Expiry Date 6 months
Supplier Images
Western Blotting (WB) image for anti-WD Repeat Domain 4 (WDR4) (AA 1-267) antibody (ABIN395139) WDR4 monoclonal antibody (M01), clone 1F9 Western Blot analysis of WDR4 expression in...
Immunohistochemistry (IHC) image for anti-WD Repeat Domain 4 (WDR4) (AA 1-267) antibody (ABIN395139) anti-WD Repeat Domain 4 (WDR4) (AA 1-267) antibody (Image 2)
Background publications Barbe, Lundberg, Oksvold et al.: "Toward a confocal subcellular atlas of the human proteome." in: Molecular & cellular proteomics : MCP, Vol. 7, Issue 3, pp. 499-508, 2008 (PubMed).

Olsen, Blagoev, Gnad et al.: "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks." in: Cell, Vol. 127, Issue 3, pp. 635-48, 2006 (PubMed).

Hu, Warnatz, Vanhecke et al.: "Cell array-based intracellular localization screening reveals novel functional features of human chromosome 21 proteins." in: BMC genomics, Vol. 7, pp. 155, 2006 (PubMed).

Rual, Venkatesan, Hao et al.: "Towards a proteome-scale map of the human protein-protein interaction network. ..." in: Nature, Vol. 437, Issue 7062, pp. 1173-8, 2005 (PubMed).

Cartlidge, Knebel, Peggie et al.: "The tRNA methylase METTL1 is phosphorylated and inactivated by PKB and RSK in vitro and in cells." in: The EMBO journal, Vol. 24, Issue 9, pp. 1696-705, 2005 (PubMed).