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Details for Product No. ABIN395143

Lysine (K)-Specific Demethylase 5B (KDM5B) antibody

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2010009J12Rik, 2210016I17Rik, AW556288, D1Ertd202e, Jarid1b, PLU-1, PUT1, Plu1, RBBP2H1A, Rb-Bp2, mKIAA4034, RGD1565602, JARID1B, CT31, PLU1, jarid1b, jarid1ba, id:ibd5050, wu:fd15c05, cb264, jarid1bb ... show more
»Alternatives Human
»Alternatives Mouse
Clonality (Clone) Monoclonal ()
»Alternatives Un-conjugated
»Alternatives ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
Pubmed 5 references available
Catalog no. ABIN395143
Quantity 0.1 mg
450.00 $   Plus shipping costs $45.00
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Availability Will be delivered in 2 to 3 Business Days
Immunogen JARID1B (NP_006609, 231 a.a. ~ 320 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 K
Clone 1G10
Isotype IgG2a kappa
Specificity JARID1B (NP_006609, 231 a.a. ~ 320 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Purification This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
Alternative Name JARID1B
Background Synonyms: Serine protease inhibitor J6, 47 kDa heat shock protein, Collagen-binding protein, Colligin, Serpin H1,Hsp47, Cbp1, Serpinh1
Molecular Weight 175645 DA
Gene ID 12406
UniProt NP_006609
Research Area Cell Structure
Application Notes ELISA ~~ 1ug/ml~3ng/ml Western blot ~~ 1:500~1000 Immunohistochemistry ~~ 1.5ug/ml
Restrictions For Research Use only
Concentration 0.5 mg/ml
Buffer PBS with 0.09% (w/v) sodium azide.
Preservative Sodium azide
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles
Expiry Date 6 months
Background publications Ehret, OConnor, Weder et al.: "Follow-up of a major linkage peak on chromosome 1 reveals suggestive QTLs associated with essential hypertension: GenNet study." in: European journal of human genetics : EJHG, Vol. 17, Issue 12, pp. 1650-7, 2009 (PubMed).

Sowa, Bennett, Gygi et al.: "Defining the human deubiquitinating enzyme interaction landscape." in: Cell, Vol. 138, Issue 2, pp. 389-403, 2009 (PubMed).

Hayami, Yoshimatsu, Veerakumarasivam et al.: "Overexpression of the JmjC histone demethylase KDM5B in human carcinogenesis: involvement in the proliferation of cancer cells through the E2F/RB pathway." in: Molecular cancer, Vol. 9, pp. 59, 2010 (PubMed).

Yao, Peng, Lin: "The flexible loop L1 of the H3K4 demethylase JARID1B ARID domain has a crucial role in DNA-binding activity." in: Biochemical and biophysical research communications, Vol. 396, Issue 2, pp. 323-8, 2010 (PubMed).

Roesch, Fukunaga-Kalabis, Schmidt et al.: "A temporarily distinct subpopulation of slow-cycling melanoma cells is required for continuous tumor growth." in: Cell, Vol. 141, Issue 4, pp. 583-94, 2010 (PubMed).

Alternatives for antigen "Lysine (K)-Specific Demethylase 5B (KDM5B)", type "Antibodies"
Hosts (17), (13)
Reactivities (28), (17), (14), (12), (12), (12), (12), (12)
Applications (17), (12), (10), (3), (2), (2), (1), (1), (1)
Conjugates (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Epitopes (3), (3), (2), (1), (1)