You are viewing an incomplete version of our website. Please click to reload the website as full version.

Kynureninase (L-Kynurenine Hydrolase) (KYNU) (AA 2-109) antibody

Details for Product No. ABIN395171, Supplier: Login to see New
Request Want additional data for this product?

The Independent Validation Initiative strives to provide you with high quality data. Find out more

Synonyms BA2753, 4432411A05Rik
AA 2-109
(6), (6), (3), (3), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1)
(46), (12), (6), (2)
(35), (14), (1), (1)
Clonality (Clone)
Monoclonal ()
ELISA, Western Blotting (WB)
(41), (17), (15), (8), (3), (3), (1), (1), (1), (1), (1)
Pubmed 5 references available
Supplier Login to see New
Catalog number from supplier Login to see New
Quantity 0.1 mg
Shipping to United States ( )
Availability Will be delivered in 8 to 11 Business Days
Immunogen KYNU (NP_003928, 2 a.a. ~ 109 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 K
Clone 1G2
Isotype IgG2a lambda
Specificity KYNU (NP_003928, 2 a.a. ~ 109 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Purification This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
Alternative Name KYNU (KYNU Antibody Abstract)
Background Synonyms: Serine protease inhibitor J6, 47 kDa heat shock protein, Collagen-binding protein, Colligin, Serpin H1,Hsp47, Cbp1, Serpinh1
Molecular Weight 52352 DA
Gene ID 12406
NCBI Accession NP_003928
Research Area Metabolism, Cell Structure
Application Notes ELISA ~~ 1ug/ml~3ng/ml Western blot ~~ 1:500~1000

Background: Kynureninase is a pyridoxal-5'-phosphate (pyridoxal-P) dependent enzyme that catalyzes the cleavage of L-kynurenine and L-3-hydroxykynurenine into anthranilic and 3-hydroxyanthranilic acids, respectively. Kynureninase is involved in the biosynthesis of NAD cofactors from tryptophan through the kynurenine pathway. Two transcript variants encoding different isoforms have been found for this gene.

Restrictions For Research Use only
Buffer PBS with 0.09% (w/v) sodium azide.
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles
Expiry Date 6 months
Supplier Images
ELISA image for anti-Kynureninase (L-Kynurenine Hydrolase) (KYNU) (AA 2-109) antibody (ABIN395171) Detection limit for recombinant GST tagged KYNU is approximately 0.1 ng/mL as a captu...
Background publications Rose, Behm, Drgon et al.: "Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score." in: Molecular medicine (Cambridge, Mass.), Vol. 16, Issue 7-8, pp. 247-53, 2010 (PubMed).

Christensen, Duno, Lund et al.: "Xanthurenic aciduria due to a mutation in KYNU encoding kynureninase." in: Journal of inherited metabolic disease, Vol. 30, Issue 2, pp. 248-55, 2007 (PubMed).

Zhang, Zhang, He et al.: "[A polymorphism of kynureninase gene in a hypertensive candidate chromosomal region is associated with essential hypertension]." in: Zhonghua xin xue guan bing za zhi, Vol. 33, Issue 7, pp. 588-91, 2005 (PubMed).

Magni, Amici, Emanuelli et al.: "Enzymology of NAD+ homeostasis in man." in: Cellular and molecular life sciences : CMLS, Vol. 61, Issue 1, pp. 19-34, 2004 (PubMed).

Strausberg, Feingold, Grouse et al.: "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. ..." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 99, Issue 26, pp. 16899-903, 2002 (PubMed).

Catalog No. ABIN395171
Plus shipping costs $45.00

Order hotline:

  • +1 877 302 8632
  • +1 888 205 9894 (TF)