anti-SAE1 antibody (SUMO1 Activating Enzyme Subunit 1) (AA 1-347)

Details for Product anti-SAE1 Antibody No. ABIN395192
Request Want additional data for this product?

The Independent Validation Initiative strives to provide you with high quality data. Find out more

Synonyms AOS1, CDGAP, HSPC140, SUA1, UBLE1A, 2400010M20Rik, 2610044L12Rik, AL033372, AW743391, D7Ertd177e, Sua1, Uble1a, Aos1p, Sua1p, aos
AA 1-347
(39), (8), (6), (6), (4), (3), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1)
(133), (31), (28), (10), (9), (3), (1), (1), (1), (1)
(85), (31), (16), (1)
Clonality (Clone)
Monoclonal ()
This SAE1 antibody is un-conjugated
(3), (3), (3), (3), (3), (3)
Immunofluorescence (IF), Western Blotting (WB)
(120), (70), (36), (26), (23), (10), (5), (4), (4), (3), (2), (1)
Pubmed 5 references available
Quantity 0.1 mg
Shipping to United States ( )
Availability Will be delivered in 8 to 11 Business Days
Immunogen SAE1 (AAH00344, 1 a.a. ~ 347 a.a) full length recombinant protein with GST tag. MW of the GST tag alone is 26 K
Clone 1G4-1G5
Isotype IgG1 lambda
Specificity SAE1 (AAH00344, 1 a.a. ~ 347 a.a) full length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Purification This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
Alternative Name SAE1 (SAE1 Antibody Abstract)
Background Synonyms: Serine protease inhibitor J6, 47 kDa heat shock protein, Collagen-binding protein, Colligin, Serpin H1,Hsp47, Cbp1, Serpinh1
Molecular Weight 38450 DA
Gene ID 12406
Research Area Cell Structure
Application Notes Western blot = 1:500-1000

Background: Posttranslational modification of proteins by the addition of the small protein SUMO (see SUMO1, MIM 601912), or sumoylation, regulates protein structure and intracellular localization. SAE1 and UBA2 (MIM 613295) form a heterodimer that functions as a SUMO-activating enzyme for the sumoylation of proteins (Okuma et al., 1999 [PubMed 9920803]).

Restrictions For Research Use only
Concentration 1 mg/ml
Buffer PBS with 0.09% (w/v) sodium azide.
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles
Expiry Date 6 months
Supplier Images
Western Blotting (WB) image for anti-SAE1 antibody (SUMO1 Activating Enzyme Subunit 1) (AA 1-347) (ABIN395192) Immunofluorescence of monoclonal antibody to SAE1 on HeLa cell (antibody concentratio...
Immunohistochemistry (IHC) image for anti-SAE1 antibody (SUMO1 Activating Enzyme Subunit 1) (AA 1-347) (ABIN395192) anti-SUMO1 Activating Enzyme Subunit 1 (SAE1) (AA 1-347) antibody (Image 2)
Background publications Ewing, Chu, Elisma et al.: "Large-scale mapping of human protein-protein interactions by mass spectrometry. ..." in: , Vol. 3, pp. 89, 2007 (PubMed).

Li, Santockyte, Shen et al.: "A general approach for investigating enzymatic pathways and substrates for ubiquitin-like modifiers." in: Archives of biochemistry and biophysics, Vol. 453, Issue 1, pp. 70-4, 2006 (PubMed).

Klenk, Humrich, Quitterer et al.: "SUMO-1 controls the protein stability and the biological function of phosducin." in: The Journal of biological chemistry, Vol. 281, Issue 13, pp. 8357-64, 2006 (PubMed).

Kimura, Wakamatsu, Suzuki et al.: "Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. ..." in: Genome research, Vol. 16, Issue 1, pp. 55-65, 2006 (PubMed).

Rual, Venkatesan, Hao et al.: "Towards a proteome-scale map of the human protein-protein interaction network. ..." in: Nature, Vol. 437, Issue 7062, pp. 1173-8, 2005 (PubMed).

Catalog No. ABIN395192
Plus shipping costs $45.00

Order hotline:

  • +1 877 302 8632
  • +1 888 205 9894 (TF)
Did you look for something else?