Search, Find and Buy Antibodies, ELISA Kits and Proteins.
Loading Loading
Order hotline:
phone +1 404 474 4654
fax +1 888 205 9894 (TF)
Details for Product No. ABIN395210

Kallikrein 10 (KLK10) antibody

Request
Want additional data for this product?

The Independent Validation Initiative strives to provide you with high quality data. Find out more

Antigen
Synonyms NES1, PRSSL1, 2300002A13Rik, KLK10
Reactivity
»Alternatives Human
Host
»Alternatives Mouse
Clonality (Clone) Monoclonal ()
Conjugate
»Alternatives Un-conjugated
Application
»Alternatives ELISA, Immunofluorescence (IF), Western Blotting (WB)
Pubmed 5 references available
Catalog no. ABIN395210
Quantity 0.05 mg
Price
450.00 $   Plus shipping costs $45.00
Shipping to
Availability Will be delivered in 2 to 3 Business Days
Immunogen KLK10 (NP_002767, 167 a.a. ~ 277 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 K
Clone 1G8
Isotype IgG1 lambda
Specificity KLK10 (NP_002767, 167 a.a. ~ 277 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Purification Purified
Alternative Name KLK10
Background Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. Its encoded protein is secreted and may play a role in suppression of tumorigenesis in breast and prostate cancers. Alternate splicing of this gene results in multiple transcript variants encoding the same protein.
Synonyms: NES1, PRSSL1 kallikrein 10
Molecular Weight 30138 DA
Gene ID 5655
UniProt NP_002767
Research Area Cancer, Cell Structure
Application Notes ELISA ~~ 1ug/ml~3ng/ml Western blot ~~ 1:500~1000 Immunofluorescence
Comment

Background: Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. Its encoded protein is secreted and may play a role in suppression of tumorigenesis in breast and prostate cancers. Alternate splicing of this gene results in multiple transcript variants encoding the same protein.

Restrictions For Research Use only
Concentration 1 mg/ml
Buffer Phosphate buffered saline, pH 7.2
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles
Expiry Date 6 months
Background publications Sardana, Diamandis: "The kallikrein family of proteins as urinary biomarkers for the detection of prostate cancer." in: Clinical biochemistry, Vol. 42, Issue 13-14, pp. 1483-6, 2009 (PubMed).

Lu, Hsieh, Lu et al.: "Aberrant DNA methylation profile and frequent methylation of KLK10 and OXGR1 genes in hepatocellular carcinoma." in: Genes, chromosomes & cancer, Vol. 48, Issue 12, pp. 1057-68, 2009 (PubMed).

Papageorgis, Lambert, Ozturk et al.: "Smad signaling is required to maintain epigenetic silencing during breast cancer progression." in: Cancer research, Vol. 70, Issue 3, pp. 968-78, 2010 (PubMed).

Klein, Halldén, Cronin et al.: "Blood biomarker levels to aid discovery of cancer-related single-nucleotide polymorphisms: kallikreins and prostate cancer." in: Cancer prevention research (Philadelphia, Pa.), Vol. 3, Issue 5, pp. 611-9, 2010 (PubMed).

Batra, Tan, OMara et al.: "Kallikrein-related peptidase 10 (KLK10) expression and single nucleotide polymorphisms in ovarian cancer survival." in: International journal of gynecological cancer : official journal of the International Gynecological Cancer Society, Vol. 20, Issue 4, pp. 529-36, 2010 (PubMed).

Alternatives for antigen "Kallikrein 10 (KLK10)", type "Antibodies"
Hosts (31), (8), (1)
Reactivities (39), (13), (12), (12)
Applications (29), (21), (10), (6), (5), (3), (2), (2), (2), (1)
Conjugates (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Epitopes (5), (4), (3), (2), (1), (1)
Beacon