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Sorting and Assembly Machinery Component 50 Homolog (SAMM50) (AA 1-469) antibody

Details for Product No. ABIN395318, Supplier: Log in to see
Antigen
  • 1110030L07Rik
  • OMP85
  • SAM50
  • samm50a
  • TOB55
  • TRG-3
  • YNL026W
  • zgc:55803
Epitope
AA 1-469
15
10
8
7
2
1
1
1
1
Reactivity
Human
38
5
5
Host
Mouse
29
9
Clonality (Clone)
Monoclonal ()
Conjugate
Un-conjugated
3
3
3
3
3
3
Application
Western Blotting (WB)
35
26
5
Supplier
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Immunogen SAMM50 (AAH07830, 1 a.a. ~ 469 a.a) full length recombinant protein with GST tag. MW of the GST tag alone is 26 K
Clone 2A9
Isotype IgG2b kappa
Specificity SAMM50 (AAH07830, 1 a.a. ~ 469 a.a) full length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Purification This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
Alternative Name SAMM50 (SAMM50 Antibody Abstract)
Background Synonyms: Serine protease inhibitor J6, 47 kDa heat shock protein, Collagen-binding protein, Colligin, Serpin H1,Hsp47, Cbp1, Serpinh1
Molecular Weight 51976 DA
Gene ID 12406
Research Area Cell Structure
Application Notes Western blot = 1:500-1000
Comment

Background: SAMM50 is a component of the sorting and assembly machinery (SAM) complex of the outer mitochondrial membrane. The SAM complex has a role in integrating beta-barrel proteins into the outer mitochondrial membrane (Humphries et al., 2005 [PubMed 15644312]).

Restrictions For Research Use only
Buffer PBS with 0.09% (w/v) sodium azide.
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles
Expiry Date 6 months
Supplier Images
Western Blotting (WB) image for anti-Sorting and Assembly Machinery Component 50 Homolog (SAMM50) (AA 1-469) antibody (ABIN395318) SAMM50 monoclonal antibody (M04), clone 2A9 Western Blot analysis of SAMM50 expressio...
Background publications Bailey, Xie, Do, Montpetit, Diaz, Mohan, Keavney, Yusuf, Gerstein, Engert, Anand: "Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study." in: Diabetes Care, Vol. 33, Issue 10, pp. 2250-3, 2010

Rose, Behm, Drgon, Johnson, Uhl: "Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score." in: Molecular medicine (Cambridge, Mass.), Vol. 16, Issue 7-8, pp. 247-53, 2010

Talmud, Drenos, Shah, Shah, Palmen, Verzilli, Gaunt, Pallas, Lovering, Li, Casas, Sofat, Kumari, Rodriguez, Johnson, Newhouse, Dominiczak, Samani, Caulfield, Sever, Stanton, Shields, Padmanabhan et al.: "Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip. ..." in: American journal of human genetics, Vol. 85, Issue 5, pp. 628-42, 2009

Yuan, Waterworth, Perry, Lim, Song, Chambers, Zhang, Vollenweider, Stirnadel, Johnson, Bergmann, Beckmann, Li, Ferrucci, Melzer, Hernandez, Singleton, Scott, Elliott, Waeber, Cardon, Frayling, Kooner, Mooser: "Population-based genome-wide association studies reveal six loci influencing plasma levels of liver enzymes." in: American journal of human genetics, Vol. 83, Issue 4, pp. 520-8, 2008

Xie, Marusich, Souda, Whitelegge, Capaldi: "The mitochondrial inner membrane protein mitofilin exists as a complex with SAM50, metaxins 1 and 2, coiled-coil-helix coiled-coil-helix domain-containing protein 3 and 6 and DnaJC11." in: FEBS letters, Vol. 581, Issue 18, pp. 3545-9, 2007