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ANKRD15 antibody (Ankyrin Repeat Domain 15) (AA 701-800)

Details for Product anti-ANKRD15 Antibody No. ABIN395383, Supplier: Log in to see
Antigen
  • A930031B09Rik
  • AU015049
  • AW121052
  • Ankrd15
  • D330024H06Rik
  • mKIAA0172
  • KANK1
  • ankrd15
  • kank1.2
  • ANKRD15
  • DMRT1
  • CPSQ2
  • KANK
  • KN motif and ankyrin repeat domains 1
  • ankyrin repeat domain 15
  • KN motif and ankyrin repeat domains 1, gene 1
  • Kank1
  • ANKRD15
  • kank1.1
  • KANK1
Alternatives
anti-Human ANKRD15 antibody for Immunoprecipitation
Epitope
AA 701-800
4
3
2
1
1
1
Reactivity
Human
21
10
8
2
2
2
1
1
Host
Mouse
17
4
Clonality (Clone)
Monoclonal ()
Application
ELISA, Western Blotting (WB)
20
13
8
5
4
2
2
1
1
Options
Supplier
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Immunogen ANKRD15 (AAH38116, 701 a.a. ~ 800 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 K
Clone 2B8
Isotype IgG2a kappa
Specificity ANKRD15 (AAH38116, 701 a.a. ~ 800 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Purification This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
Alternative Name ANKRD15 (ANKRD15 Antibody Abstract)
Background Synonyms: Serine protease inhibitor J6, 47 kDa heat shock protein, Collagen-binding protein, Colligin, Serpin H1,Hsp47, Cbp1, Serpinh1
Molecular Weight 147289 DA
Gene ID 12406
Research Area Cancer, Cell Structure
Pathways Regulation of Actin Filament Polymerization
Application Notes ELISA ~~ 1ug/ml~3ng/ml Western blot ~~ 1:500~1000
Comment

Background: This gene encodes a protein containing four ankyrin repeat domains in its C-terminus. The suggested role for this protein is in tumorigenesis of renal cell carcinoma. Two alternatively spliced transcript variants encoding different isoforms have been identified.

Restrictions For Research Use only
Buffer PBS with 0.09% (w/v) sodium azide.
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles
Expiry Date 6 months
Supplier Images
ELISA image for anti-ANKRD15 antibody (Ankyrin Repeat Domain 15) (AA 701-800) (ABIN395383) Detection limit for recombinant GST tagged ANKRD15 is approximately 0.1 ng/mL as a ca...
Background publications Rose, Behm, Drgon, Johnson, Uhl: "Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score." in: Molecular medicine (Cambridge, Mass.), Vol. 16, Issue 7-8, pp. 247-53, 2010 (PubMed).

Medves, Duhoux, Ferrant, Toffalini, Ameye, Libouton, Poirel, Demoulin: "KANK1, a candidate tumor suppressor gene, is fused to PDGFRB in an imatinib-responsive myeloid neoplasm with severe thrombocythemia." in: Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K, Vol. 24, Issue 5, pp. 1052-5, 2010 (PubMed).

Hoppenbrouwers, Aulchenko, Janssens, Ramagopalan, Broer, Kayser, Ebers, Oostra, van Duijn, Hintzen: "Replication of CD58 and CLEC16A as genome-wide significant risk genes for multiple sclerosis." in: Journal of human genetics, Vol. 54, Issue 11, pp. 676-80, 2009 (PubMed).

Kakinuma, Kiyama: "A major mutation of KIF21A associated with congenital fibrosis of the extraocular muscles type 1 (CFEOM1) enhances translocation of Kank1 to the membrane." in: Biochemical and biophysical research communications, Vol. 386, Issue 4, pp. 639-44, 2009 (PubMed).

DNetto, Ward, Morrison, Ramagopalan, Dyment, DeLuca, Handunnetthi, Sadovnick, Ebers: "Risk alleles for multiple sclerosis in multiplex families." in: Neurology, Vol. 72, Issue 23, pp. 1984-8, 2009 (PubMed).