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Details for Product No. ABIN395383

Ankyrin Repeat Domain 15 (ANKRD15) antibody

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Antigen
Synonyms ANKRD15, CPSQ2, KANK, A930031B09Rik, AU015049, AW121052, Ankrd15, D330024H06Rik, mKIAA0172, KANK1, ankrd15, kank1.2, DMRT1
Reactivity
»Alternatives Human
Host
»Alternatives Mouse
Clonality (Clone) Monoclonal ()
Application
»Alternatives ELISA, Western Blotting (WB)
Pubmed 5 references available
Catalog no. ABIN395383
Quantity 0.1 mg
Price
450.00 $   Plus shipping costs $45.00
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Immunogen ANKRD15 (AAH38116, 701 a.a. ~ 800 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 K
Clone 2B8
Isotype IgG2a kappa
Specificity ANKRD15 (AAH38116, 701 a.a. ~ 800 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Purification This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
Alternative Name ANKRD15
Background Synonyms: Serine protease inhibitor J6, 47 kDa heat shock protein, Collagen-binding protein, Colligin, Serpin H1,Hsp47, Cbp1, Serpinh1
Molecular Weight 147289 DA
Gene ID 12406
Research Area Cancer, Cell Structure
Application Notes ELISA ~~ 1ug/ml~3ng/ml Western blot ~~ 1:500~1000
Comment

Background: This gene encodes a protein containing four ankyrin repeat domains in its C-terminus. The suggested role for this protein is in tumorigenesis of renal cell carcinoma. Two alternatively spliced transcript variants encoding different isoforms have been identified.

Restrictions For Research Use only
Buffer PBS with 0.09% (w/v) sodium azide.
Preservative Sodium azide
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles
Expiry Date 6 months
Background publications DNetto, Ward, Morrison et al.: "Risk alleles for multiple sclerosis in multiplex families." in: Neurology, Vol. 72, Issue 23, pp. 1984-8, 2009 (PubMed).

Kakinuma, Kiyama: "A major mutation of KIF21A associated with congenital fibrosis of the extraocular muscles type 1 (CFEOM1) enhances translocation of Kank1 to the membrane." in: Biochemical and biophysical research communications, Vol. 386, Issue 4, pp. 639-44, 2009 (PubMed).

Hoppenbrouwers, Aulchenko, Janssens et al.: "Replication of CD58 and CLEC16A as genome-wide significant risk genes for multiple sclerosis." in: Journal of human genetics, Vol. 54, Issue 11, pp. 676-80, 2009 (PubMed).

Medves, Duhoux, Ferrant et al.: "KANK1, a candidate tumor suppressor gene, is fused to PDGFRB in an imatinib-responsive myeloid neoplasm with severe thrombocythemia." in: Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K, Vol. 24, Issue 5, pp. 1052-5, 2010 (PubMed).

Rose, Behm, Drgon et al.: "Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score." in: Molecular medicine (Cambridge, Mass.), Vol. 16, Issue 7-8, pp. 247-53, 2010 (PubMed).

Alternatives for antigen "Ankyrin Repeat Domain 15 (ANKRD15)", type "Antibodies"
Hosts (4), (1)
Reactivities (5), (3), (2)
Applications (5), (4), (3), (1), (1)
Epitopes (1), (1)
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