You are viewing an incomplete version of our website. Please click to reload the website as full version.

CXCR5 antibody (Chemokine (C-X-C Motif) Receptor 5) (AA 1-56)

Details for Product anti-CXCR5 Antibody No. ABIN395397, Supplier: Log in to see
Antigen
  • BLR1
  • CRL1
  • CD185
  • MDR15
  • Blr1
  • CXC-R5
  • CXCR-5
  • Gpcr6
  • NLR
  • chemokine (C-X-C motif) receptor 5
  • CXCR5
  • Cxcr5
Epitope
AA 1-56
22
19
19
15
14
8
3
2
2
2
2
2
1
1
1
1
1
1
1
1
1
Reactivity
Human
166
57
22
3
1
1
1
1
1
Host
Mouse
86
78
35
2
Clonality (Clone)
Monoclonal ()
Conjugate
This CXCR5 antibody is un-conjugated
12
9
9
7
7
7
6
6
6
4
4
4
4
4
3
3
3
2
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
Application
ELISA, Western Blotting (WB)
108
66
27
27
21
13
11
9
9
6
6
4
2
2
2
1
1
1
Options
Supplier
Log in to see
Supplier Product No.
Log in to see
Request

Get this product for free

It's quick and easy to submit your validation proposal. I want to validate this product

Learn more

Available images

Immunogen BLR1 (NP_001707, 1 a.a. ~ 56 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 K
Clone 2C1
Isotype IgG2a kappa
Specificity BLR1 (NP_001707, 1 a.a. ~ 56 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Purification This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
Alternative Name BLR1 (CXCR5 Antibody Abstract)
Background Synonyms: Serine protease inhibitor J6, 47 kDa heat shock protein, Collagen-binding protein, Colligin, Serpin H1,Hsp47, Cbp1, Serpinh1
Molecular Weight 41955 DA
Gene ID 12406
NCBI Accession NP_001707
Research Area Cell Structure, Cancer
Application Notes ELISA ~~ 1ug/ml~3ng/ml Western blot ~~ 1:500~1000
Comment

Background: This gene was identified as a gene specifically expressed in Burkitt's lymphoma and lymphatic tissues. The protein encoded by this gene is predicted to be a seven transmembrane G protein- coupled receptor and belongs to the CXC chemokine receptor family. BLC, a B-lymphocyte chemoattractant, was identified to be a specific ligand for this receptor. Studies of this gene and its mouse conterpart strongly suggest the essential function of this gene in B cell migration and localization within specific anatomic compartments, such as follicles in lymph nodes as well as in spleen. Two alternatively spliced variants of this gene exist.

Restrictions For Research Use only
Buffer PBS with 0.09% (w/v) sodium azide.
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles
Expiry Date 6 months
Supplier Images
ELISA image for anti-CXCR5 antibody (Chemokine (C-X-C Motif) Receptor 5) (AA 1-56) (ABIN395397) Detection limit for recombinant GST tagged BLR1 is approximately 0.03 ng/mL as a capt...
Background publications Bailey, Xie, Do, Montpetit, Diaz, Mohan, Keavney, Yusuf, Gerstein, Engert, Anand: "Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study." in: Diabetes Care, Vol. 33, Issue 10, pp. 2250-3, 2010 (PubMed).

El Haibi, Sharma, Singh, Johnson, Suttles, Singh, Lillard: "PI3Kp110-, Src-, FAK-dependent and DOCK2-independent migration and invasion of CXCL13-stimulated prostate cancer cells." in: Molecular cancer, Vol. 9, pp. 85, 2010 (PubMed).

Lee, Shiao, Wu, Chen, Hsu, Tsai, Tsai: "Serum BLC/CXCL13 concentrations and renal expression of CXCL13/CXCR5 in patients with systemic lupus erythematosus and lupus nephritis." in: The Journal of rheumatology, Vol. 37, Issue 1, pp. 45-52, 2009 (PubMed).

Talmud, Drenos, Shah, Shah, Palmen, Verzilli, Gaunt, Pallas, Lovering, Li, Casas, Sofat, Kumari, Rodriguez, Johnson, Newhouse, Dominiczak, Samani, Caulfield, Sever, Stanton, Shields, Padmanabhan et al.: "Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip. ..." in: American journal of human genetics, Vol. 85, Issue 5, pp. 628-42, 2009 (PubMed).

Singh, Singh, Singh, Rai, Novakovic, Chung, Didier, Grizzle, Lillard: "Clinical and biological significance of CXCR5 expressed by prostate cancer specimens and cell lines." in: International journal of cancer. Journal international du cancer, Vol. 125, Issue 10, pp. 2288-95, 2009 (PubMed).