Ectonucleoside Triphosphate diphosphohydrolase 6 (ENTPD6) antibody

Antigen: Ectonucleoside Triphosphate diphosphohydrolase 6 (ENTPD6)

Synonyms: CD39L2, IL6ST2, IL-6SAG, FLJ36711, NTPDase-6, dJ738P15.3, DKFZp781G2277, DKFZp781K21102, Cd39l2, 2700026H11Rik, ENTPD6, MGC127592, entpd6, zgc:110701

Clonality: Monoclonal (2D10)

Host: Mouse

Reactivity: Human

Application: ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)

Certificates: ISO 9001:2008

Catalog no.: ABIN395477

Additional Information

Alternative name: ENTPD6

Gene ID: 955

UniProt: NP_001238

Immunogen: ENTPD6 (NP_001238, 386 a.a. ~ 485 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 K

Isotype: IgG2a kappa

Clone: 2D10

Description: Other names: CD39L2, IL6SAG, IL6ST2, NTPDase6, dJ738P15.3 ectonucleoside triphosphate diphosphohydrolase 6 (putative function)

Characteristics: Purified Mouse Monoclonal Antibody (Mab)

Specificity: ENTPD6 (NP_001238, 386 a.a. ~ 485 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Molecular Weight: 53247 DA

Comments:

Background: ENTPD6 is similar to E-type nucleotidases (NTPases). NTPases, such as CD39, mediate catabolism of extracellular nucleotides. ENTPD6 contains 4 apyrase-conserved regions which is characteristic of NTPases. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Application Details

Application Notes: ELISA ~~ 1ug/ml~3ng/ml Western blot ~~ 1:500~1000 Immunohistochemistry ~~ 1.5ug/ml

Purification: Purified

Buffer: Clear, colorless solution in phosphate buffered saline, pH 7.2 .

Storage: Maintain refrigerated at 2-8 deg C for up to 6 months. For long term storage store at -20 deg C in small aliquots to prevent freeze-thaw cycles

Research Area: Metabolism, Cell Structure

Restrictions: For Research Use only

Images

Immunoperoxidase of monoclonal antibody to ENTPD6 ( Cat # AT1917a ) on formalin-fixed paraffin-embedded human small Intestine. [antibody concentration 3 ug/ml]

Publications

Product: Otsuki, Ota, Nishikawa et al.: "Signal sequence and keyword trap in silico for selection of full-length human cDNAs encoding secretion or membrane proteins from oligo-capped cDNA libraries." in: DNA research : an international journal for rapid publication of reports on genes and genomes, Vol. 12, Issue 2, pp. 117-26, 2005 (PubMed).

Mehrle, Rosenfelder, Schupp et al.: "The LIFEdb database in 2006." in: Nucleic acids research, Vol. 34, Issue Database issue, pp. D415-8, 2005 (PubMed).

Lim, Hao, Shaw et al.: "A protein-protein interaction network for human inherited ataxias and disorders of Purkinje cell degeneration." in: Cell, Vol. 125, Issue 4, pp. 801-14, 2006 (PubMed).

Talmud, Drenos, Shah et al.: "Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip." in: American journal of human genetics, Vol. 85, Issue 5, pp. 628-42, 2009 (PubMed).

Bailey, Xie, Do et al.: "Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study." in: Diabetes Care, Vol. 33, Issue 10, pp. 2250-3, 2010 (PubMed).