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YAP1 antibody (Yes-Associated Protein 1) (AA 53-162)

Details for Product anti-YAP1 Antibody No. ABIN395579, Supplier: Log in to see
Antigen
  • YAP1
  • YAP
  • YAP2
  • YAP65
  • YKI
  • AI325207
  • Yap
  • Yap65
  • Yki
  • Yorkie
  • cb194
  • sb:cb194
  • si:ch211-181p1.5
  • si:dkey-3b8.3
  • wu:fc18c04
  • zgc:158380
  • xyap
  • yap
  • yap2
  • yap65
  • yki
  • HCCA1
  • HCCA2
  • YY1AP
  • Yes-associated protein 1
  • Yes-associated protein 1, 65kDa
  • yes-associated protein 1
  • YY1 associated protein 1
  • YAP1
  • LOC787360
  • LOC100219556
  • Yap1
  • yap1
  • YY1AP1
Alternatives
anti-Human YAP1 antibody for Western Blotting
Epitope
AA 53-162
21
19
18
15
15
14
13
12
9
9
7
7
6
5
3
2
2
2
1
1
1
1
1
1
1
1
1
Reactivity
Human
228
91
78
7
5
5
5
4
2
2
2
2
2
2
1
Host
Mouse
158
59
11
1
Clonality (Clone)
Monoclonal ()
Conjugate
This YAP1 antibody is un-conjugated
9
8
8
7
6
6
3
3
2
2
2
2
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
Application
Immunofluorescence (IF), Western Blotting (WB)
173
110
59
54
39
37
26
25
17
12
6
3
3
2
1
1
Options
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Available images

Immunogen YAP1 (NP_006097, 53 a.a. ~ 162 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 K
Clone 2F12
Isotype IgG2a kappa
Specificity YAP1 (NP_006097, 53 a.a. ~ 162 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Purification This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
Alternative Name YAP1 (YAP1 Antibody Abstract)
Molecular Weight 48755 DA
NCBI Accession NM_006106
UniProt P46937
Research Area Cell Signaling, Cell Structure
Pathways MAPK Signaling, Stem Cell Maintenance, Regulation of Lipid Metabolism by PPARalpha
Application Notes Western blot = 1:500-1000
Comment

Background: This gene encodes the human ortholog of chicken YAP protein which binds to the SH3 domain of the Yes proto-oncogene product. This protein contains a WW domain that is found in various structural, regulatory and signaling molecules in yeast, nematode, and mammals, and may be involved in protein-protein interaction.

Restrictions For Research Use only
Concentration 0.5 mg/ml
Buffer PBS with 0.09% (w/v) sodium azide.
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles
Expiry Date 6 months
Supplier Images
Western Blotting (WB) image for anti-YAP1 antibody (Yes-Associated Protein 1) (AA 53-162) (ABIN395579) Immunofluorescence of monoclonal antibody to YAP1 on HeLa cell (antibody concentratio...
Immunohistochemistry (IHC) image for anti-YAP1 antibody (Yes-Associated Protein 1) (AA 53-162) (ABIN395579) anti-Yes-Associated Protein 1 (YAP1) (AA 53-162) antibody (Image 2)
Background publications Rose, Behm, Drgon, Johnson, Uhl: "Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score." in: Molecular medicine (Cambridge, Mass.), Vol. 16, Issue 7-8, pp. 247-53, 2010 (PubMed).

Liu, Poon, Luk: "MicroRNA-375 targets Hippo-signaling effector YAP in liver cancer and inhibits tumor properties." in: Biochemical and biophysical research communications, Vol. 394, Issue 3, pp. 623-7, 2010 (PubMed).

Wang, Dong, Zhang, Li, Wang, Qiu: "Overexpression of yes-associated protein contributes to progression and poor prognosis of non-small-cell lung cancer." in: Cancer science, Vol. 101, Issue 5, pp. 1279-85, 2010 (PubMed).

Watt, Judson, Medlow, Reid, Kurth, Burniston, Ratkevicius, De Bari, Wackerhage: "Yap is a novel regulator of C2C12 myogenesis." in: Biochemical and biophysical research communications, Vol. 393, Issue 4, pp. 619-24, 2010 (PubMed).

Zhao, Li, Tumaneng, Wang, Guan: "A coordinated phosphorylation by Lats and CK1 regulates YAP stability through SCF(beta-TRCP)." in: Genes & development, Vol. 24, Issue 1, pp. 72-85, 2010 (PubMed).