Yes-Associated Protein 1 (YAP1) (AA 53-162) antibody

Details for Product No. ABIN395579
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Antigen
Synonyms YAP1, YAP, YAP2, YAP65, YKI, AI325207, Yap, Yap65, Yki, Yorkie, cb194, sb:cb194, si:ch211-181p1.5, si:dkey-3b8.3, wu:fc18c04, zgc:158380, xyap, yap, yap2, yap65, yki, HCCA1, HCCA2, YY1AP
Epitope
AA 53-162
(22), (18), (13), (12), (12), (12), (12), (8), (7), (6), (5), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity
Human
(161), (61), (58), (3), (2), (2), (1), (1), (1), (1), (1)
Host
Mouse
(132), (23), (8)
Clonality (Clone)
Monoclonal ()
Conjugate
Un-conjugated
(7), (6), (6), (5), (5), (5), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1)
Application
Immunofluorescence (IF), Western Blotting (WB)
(129), (75), (40), (32), (28), (20), (17), (12), (9), (6), (6), (2), (1), (1), (1), (1)
Pubmed 5 references available
Quantity 0.1 mg
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Immunogen YAP1 (NP_006097, 53 a.a. ~ 162 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 K
Clone 2F12
Isotype IgG2a kappa
Specificity YAP1 (NP_006097, 53 a.a. ~ 162 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Purification This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
Alternative Name YAP1 (YAP1 Antibody Abstract)
Molecular Weight 48755 DA
NCBI Accession NM_006106
UniProt P46937
Research Area Cell Signaling, Cell Structure
Application Notes Western blot = 1:500-1000
Comment

Background: This gene encodes the human ortholog of chicken YAP protein which binds to the SH3 domain of the Yes proto-oncogene product. This protein contains a WW domain that is found in various structural, regulatory and signaling molecules in yeast, nematode, and mammals, and may be involved in protein-protein interaction.

Restrictions For Research Use only
Concentration 0.5 mg/ml
Buffer PBS with 0.09% (w/v) sodium azide.
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles
Expiry Date 6 months
Supplier Images
anti-Yes-Associated Protein 1 (YAP1) (AA 53-162) antibody Immunofluorescence of monoclonal antibody to YAP1 on HeLa cell (antibody concentratio...
anti-Yes-Associated Protein 1 (YAP1) (AA 53-162) antibody (2) anti-Yes-Associated Protein 1 (YAP1) (AA 53-162) antibody (Image 2)
Background publications Rose, Behm, Drgon et al.: "Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score." in: Molecular medicine (Cambridge, Mass.), Vol. 16, Issue 7-8, pp. 247-53, 2010 (PubMed).

Liu, Poon, Luk: "MicroRNA-375 targets Hippo-signaling effector YAP in liver cancer and inhibits tumor properties." in: Biochemical and biophysical research communications, Vol. 394, Issue 3, pp. 623-7, 2010 (PubMed).

Wang, Dong, Zhang et al.: "Overexpression of yes-associated protein contributes to progression and poor prognosis of non-small-cell lung cancer." in: Cancer science, Vol. 101, Issue 5, pp. 1279-85, 2010 (PubMed).

Watt, Judson, Medlow et al.: "Yap is a novel regulator of C2C12 myogenesis." in: Biochemical and biophysical research communications, Vol. 393, Issue 4, pp. 619-24, 2010 (PubMed).

Zhao, Li, Tumaneng et al.: "A coordinated phosphorylation by Lats and CK1 regulates YAP stability through SCF(beta-TRCP)." in: Genes & development, Vol. 24, Issue 1, pp. 72-85, 2010 (PubMed).

Validation Images
Catalog No. ABIN395579
450.00 $
Plus shipping costs $45.00
Quantity
Price
0.1 mg
450.00 $

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