Phospholipid Transfer Protein (PLTP) antibody

Details for Product No. ABIN395590
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Synonyms BPIFE, HDLCQ9, Bpife, OD107, zgc:100903, MGC84445, PLTP, hdlcq9, DKFZp469A1437
(40), (22), (15), (12), (12)
(37), (6), (2)
Clonality (Clone)
Monoclonal ()
(2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Western Blotting (WB)
(34), (18), (13), (10), (7), (7), (6), (3), (2), (2), (1), (1)
Pubmed 5 references available
Catalog no. ABIN395590
Quantity 0.1 mg
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Immunogen PLTP (AAH05045, 1 a.a. ~ 422 a.a) full length recombinant protein with GST tag. MW of the GST tag alone is 26 K
Clone 2F3-G4
Isotype IgG1 kappa
Specificity PLTP (AAH05045, 1 a.a. ~ 422 a.a) full length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Purification This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
Alternative Name PLTP
Background Synonyms: Serine protease inhibitor J6, 47 kDa heat shock protein, Collagen-binding protein, Colligin, Serpin H1,Hsp47, Cbp1, Serpinh1
Molecular Weight NONE?! DA
Gene ID 12406
Research Area Metabolism, Cell Structure
Application Notes Western blot = 1:500-1000

Background: The protein encoded by this gene is one of at least two lipid transfer proteins found in human plasma. The encoded protein transfers phospholipids from triglyceride-rich lipoproteins to high density lipoprotein (HDL). In addition to regulating the size of HDL particles, this protein may be involved in cholesterol metabolism. At least two transcript variants encoding different isoforms have been found for this gene.

Restrictions For Research Use only
Buffer PBS with 0.09% (w/v) sodium azide.
Preservative Sodium azide
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles
Expiry Date 6 months
Supplier Images
anti-Phospholipid Transfer Protein (PLTP) antibody PLTP monoclonal antibody (M01), clone 2F3-G4 Western Blot analysis of PLTP expression in Hela NE on formalin-fixed paraffin-embedded human ovary, clear cell carcinoma tissue (antibody concentration 5 µg/mL).
anti-Phospholipid Transfer Protein (PLTP) antibody (2) anti-Phospholipid Transfer Protein (PLTP) antibody (Image 2)
Background publications Robciuc, Metso, Sima et al.: "Human apoA-I increases macrophage foam cell derived PLTP activity without affecting the PLTP mass." in: Lipids in health and disease, Vol. 9, pp. 59, 2010 (PubMed).

Fontaine-Bisson, Renström, Rolandsson et al.: "Evaluating the discriminative power of multi-trait genetic risk scores for type 2 diabetes in a northern Swedish population." in: Diabetologia, Vol. 53, Issue 10, pp. 2155-62, 2010 (PubMed).

Bailey, Xie, Do et al.: "Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study." in: Diabetes Care, Vol. 33, Issue 10, pp. 2250-3, 2010 (PubMed).

Vergeer, Boekholdt, Sandhu et al.: "Genetic variation at the phospholipid transfer protein locus affects its activity and high-density lipoprotein size and is a novel marker of cardiovascular disease susceptibility." in: Circulation, Vol. 122, Issue 5, pp. 470-7, 2010 (PubMed).

Kuerban, Shibata, Komatsu et al.: "Genetic association between PLTP gene polymorphisms and Alzheimer's disease in a Japanese population." in: Dementia and geriatric cognitive disorders, Vol. 30, Issue 1, pp. 78-82, 2010 (PubMed).

Hosts (37), (6), (2)
Reactivities (40), (22), (15), (12), (12)
Applications (34), (18), (13), (10), (7), (7), (6), (3), (2), (2), (1), (1)
Conjugates (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Epitopes (5), (2), (2), (2), (2), (1), (1)
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