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S100 Calcium Binding Protein A11 (S100A11) (AA 1-106) antibody

Details for Product No. ABIN395596, Supplier: Log in to see
Antigen
  • MLN70
  • S100C
  • PCALG
  • EMAPI
  • Emap1
  • S100a14
  • S100c
  • cal
Epitope
AA 1-106
18
14
6
6
5
5
3
3
2
2
2
1
1
1
1
1
1
1
1
Reactivity
Human
81
18
12
8
6
2
2
Host
Mouse
80
9
8
8
1
Clonality (Clone)
Monoclonal ()
Conjugate
Un-conjugated
12
10
4
4
4
4
1
Application
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), ELISA, Western Blotting (WB)
76
71
38
14
12
10
6
5
2
2
1
1
1
1
1
1
Supplier
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Immunogen S100A11 (AAH14354, 1 a.a. ~ 106 a.a) full length recombinant protein with GST tag. MW of the GST tag alone is 26 K
Clone 2F4
Isotype IgG2a kappa
Specificity S100A11 (AAH14354, 1 a.a. ~ 106 a.a) full length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Purification This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
Alternative Name S100A11 (S100A11 Antibody Abstract)
Background Synonyms: Serine protease inhibitor J6, 47 kDa heat shock protein, Collagen-binding protein, Colligin, Serpin H1,Hsp47, Cbp1, Serpinh1
Molecular Weight 11740 DA
Gene ID 12406
Research Area Cancer, Cell Structure
Pathways
Application Notes ELISA ~~ 1ug/ml~3ng/ml Western blot ~~ 1:500~1000 Immunohistochemistry ~~ 1.5ug/ml
Comment

Background: The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein may function in motility, invasion, and tubulin polymerization. Chromosomal rearrangements and altered expression of this gene have been implicated in tumor metastasis.

Restrictions For Research Use only
Concentration 0.5 mg/ml
Buffer PBS with 0.09% (w/v) sodium azide.
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles
Expiry Date 6 months
Supplier Images
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) image for anti-S100 Calcium Binding Protein A11 (S100A11) (AA 1-106) antibody (ABIN395596) Immunoperoxidase of monoclonal antibody to S100A11 on formalin-fixed paraffin-embedde...
Immunohistochemistry (IHC) image for anti-S100 Calcium Binding Protein A11 (S100A11) (AA 1-106) antibody (ABIN395596) anti-S100 Calcium Binding Protein A11 (S100A11) (AA 1-106) antibody (Image 2)
Background publications Rose, Behm, Drgon et al.: "Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score." in: Molecular medicine (Cambridge, Mass.), Vol. 16, Issue 7-8, pp. 247-53, 2010 (PubMed).

Liu, Wang, Li et al.: "Ca2+-binding protein S100A11: a novel diagnostic marker for breast carcinoma." in: Oncology reports, Vol. 23, Issue 5, pp. 1301-8, 2010 (PubMed).

Marlatt, Spratt, Shaw: "Codon optimization for enhanced Escherichia coli expression of human S100A11 and S100A1 proteins." in: Protein expression and purification, Vol. 73, Issue 1, pp. 58-64, 2010 (PubMed).

Medland, Nyholt, Painter et al.: "Common variants in the trichohyalin gene are associated with straight hair in Europeans." in: American journal of human genetics, Vol. 85, Issue 5, pp. 750-5, 2009 (PubMed).

Bin, Howell, Kim et al.: "Inhibition of S100A11 gene expression impairs keratinocyte response against vaccinia virus through downregulation of the IL-10 receptor 2 chain." in: The Journal of allergy and clinical immunology, Vol. 124, Issue 2, pp. 270-7, 277.e1, 2009 (PubMed).