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Acetyl-CoA Acyltransferase 2 (ACAA2) (AA 151-261) antibody

Details for Product No. ABIN395615, Supplier: Log in to see
Antigen
  • DSAEC
  • 0610011L04Rik
  • AI255831
  • AI265397
  • D18Ertd240e
Epitope
AA 151-261
4
3
2
1
Reactivity
Human
39
21
18
6
6
2
2
2
2
Host
Mouse
22
20
Clonality (Clone)
Monoclonal ()
Application
Western Blotting (WB)
38
21
19
11
7
1
Supplier
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Immunogen ACAA2 (NP_006102, 151 a.a. ~ 261 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 K
Clone 2F7
Isotype IgG1 kappa
Specificity ACAA2 (NP_006102, 151 a.a. ~ 261 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Purification This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
Alternative Name ACAA2 (ACAA2 Antibody Abstract)
Background Synonyms: Serine protease inhibitor J6, 47 kDa heat shock protein, Collagen-binding protein, Colligin, Serpin H1,Hsp47, Cbp1, Serpinh1
Molecular Weight 41924 DA
Gene ID 12406
NCBI Accession NP_006102
Research Area Cell Structure
Application Notes Western blot = 1:500-1000
Comment

Background: The encoded protein catalyzes the last step of the mitochondrial fatty acid beta-oxidation spiral. Unlike most mitochondrial matrix proteins, it contains a non-cleavable amino-terminal targeting signal.

Restrictions For Research Use only
Buffer PBS with 0.09% (w/v) sodium azide.
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles
Expiry Date 6 months
Supplier Images
Western Blotting (WB) image for anti-Acetyl-CoA Acyltransferase 2 (ACAA2) (AA 151-261) antibody (ABIN395615) ACAA2 monoclonal antibody (M05), clone 2F7. Western Blot analysis of ACAA2 expression...
Background publications Hu, Lui, Mak et al.: "Pharmacogenetic analysis of lipid responses to rosuvastatin in Chinese patients." in: Pharmacogenetics and genomics, Vol. 20, Issue 10, pp. 634-7, 2010 (PubMed).

Fontaine-Bisson, Renström, Rolandsson et al.: "Evaluating the discriminative power of multi-trait genetic risk scores for type 2 diabetes in a northern Swedish population." in: Diabetologia, Vol. 53, Issue 10, pp. 2155-62, 2010 (PubMed).

Cao, Liu, Tang et al.: "Acetyl-Coenzyme A acyltransferase 2 attenuates the apoptotic effects of BNIP3 in two human cell lines." in: Biochimica et biophysica acta, Vol. 1780, Issue 6, pp. 873-80, 2008 (PubMed).

Kathiresan, Melander, Guiducci et al.: "Six new loci associated with blood low-density lipoprotein cholesterol, high-density lipoprotein cholesterol or triglycerides in humans. ..." in: Nature genetics, Vol. 40, Issue 2, pp. 189-97, 2008 (PubMed).

Willer, Sanna, Jackson et al.: "Newly identified loci that influence lipid concentrations and risk of coronary artery disease." in: Nature genetics, Vol. 40, Issue 2, pp. 161-9, 2008 (PubMed).