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Acyl-CoA Binding Domain Containing 3 (Acbd3) (AA 73-172) antibody

Details for Product No. ABIN395659, Supplier: Log in to see
Antigen
  • 60kDa
  • 8430407O11Rik
  • ACBD3
  • acbd3
  • acyl-CoA-binding domain 3
  • cb366
  • D1Ertd10e
  • fa20g08
  • GCP60
  • Gocap1
  • GOCAP1
  • GOLPH1
  • MGC122176
  • PAP7
  • Pap7
  • sb:cb366
  • si:dkey-267p15.1
  • T22A6.60
  • T22A6_60
  • wu:fa04b12
  • wu:fa20g08
  • wu:fd14b03
  • wu:fi29h06
  • zgc:66303
Epitope
AA 73-172
11
10
5
5
4
2
1
1
Reactivity
Human
69
26
10
3
3
Host
Mouse
36
34
Clonality (Clone)
Monoclonal ()
Conjugate
Un-conjugated
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
Application
Immunofluorescence (IF), Western Blotting (WB)
58
26
20
12
12
11
11
7
2
1
Supplier
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Immunogen ACBD3 (NP_073572, 73 a.a. ~ 172 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 K
Clone 2G2
Isotype IgG1 kappa
Specificity ACBD3 (NP_073572, 73 a.a. ~ 172 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Purification This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
Alternative Name ACBD3 (Acbd3 Antibody Abstract)
Background Synonyms: Serine protease inhibitor J6, 47 kDa heat shock protein, Collagen-binding protein, Colligin, Serpin H1,Hsp47, Cbp1, Serpinh1
Molecular Weight 60593 DA
Gene ID 12406
NCBI Accession NP_073572
Research Area Cell Structure
Application Notes Western blot = 1:500-1000
Comment

Background: The Golgi complex plays a key role in the sorting and modification of proteins exported from the endoplasmic reticulum. The protein encoded by this gene is involved in the maintenance of Golgi structure and function through its interaction with the integral membrane protein giantin. It may also be involved in the hormonal regulation of steroid formation.

Restrictions For Research Use only
Buffer PBS with 0.09% (w/v) sodium azide.
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles
Expiry Date 6 months
Supplier Images
Western Blotting (WB) image for anti-Acyl-CoA Binding Domain Containing 3 (Acbd3) (AA 73-172) antibody (ABIN395659) Immunofluorescence of monoclonal antibody to ACBD3 on HeLa cell (antibody concentrati...
Immunohistochemistry (IHC) image for anti-Acyl-CoA Binding Domain Containing 3 (Acbd3) (AA 73-172) antibody (ABIN395659) anti-Acyl-CoA Binding Domain Containing 3 (Acbd3) (AA 73-172) antibody (Image 2)
Background publications Skibola, Bracci, Halperin, Nieters, Hubbard, Paynter, Skibola, Agana, Becker, Tressler, Forrest, Sankararaman, Conde, Holly, Smith: "Polymorphisms in the estrogen receptor 1 and vitamin C and matrix metalloproteinase gene families are associated with susceptibility to lymphoma." in: PLoS ONE, Vol. 3, Issue 7, pp. e2816, 2008

Barbe, Lundberg, Oksvold, Stenius, Lewin, Björling, Asplund, Pontén, Brismar, Uhlén, Andersson-Svahn: "Toward a confocal subcellular atlas of the human proteome." in: Molecular & cellular proteomics : MCP, Vol. 7, Issue 3, pp. 499-508, 2008

Sbodio, Machamer: "Identification of a redox-sensitive cysteine in GCP60 that regulates its interaction with golgin-160." in: The Journal of biological chemistry, Vol. 282, Issue 41, pp. 29874-81, 2007

Sbodio, Hicks, Simon, Machamer: "GCP60 preferentially interacts with a caspase-generated golgin-160 fragment." in: The Journal of biological chemistry, Vol. 281, Issue 38, pp. 27924-31, 2006

Gregory, Barlow, McLay, Kaul, Swarbreck, Dunham, Scott, Howe, Woodfine, Spencer, Jones, Gillson, Searle, Zhou, Kokocinski, McDonald, Evans, Phillips, Atkinson, Cooper, Jones, Hall, Andrews, Lloyd et al.: "The DNA sequence and biological annotation of human chromosome 1. ..." in: Nature, Vol. 441, Issue 7091, pp. 315-21, 2006