Armadillo Repeat Containing, X-Linked 3 (ARMCX3) antibody

Antigen: Armadillo Repeat Containing, X-Linked 3 (ARMCX3)

Synonyms: ALEX3, KIAA0443, MGC12199, dJ545K15.2, DKFZp781N1954, AI450003, 1200004E24Rik, ARMCX3, DKFZp459E2029

Clonality: Monoclonal (2G3)

Host: Mouse

Reactivity: Human

Conjugate: Un-conjugated

Application: ELISA, Western Blotting (WB)

Certificates: ISO 9001:2008

Catalog no.: ABIN395662

Additional Information

Alternative name: ARMCX3

Gene ID: 51566

UniProt: NP_057691

Immunogen: ARMCX3 (NP_057691, 278 a.a. ~ 380 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 K

Isotype: IgG2a kappa

Clone: 2G3

Description: Other names: ALEX3, DKFZp781N1954, KIAA0443, MGC12199, dJ545K15.2 armadillo repeat containing, X-linked 3

Characteristics: Purified Mouse Monoclonal Antibody (Mab)

Specificity: ARMCX3 (NP_057691, 278 a.a. ~ 380 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Molecular Weight: 42501 DA

Comments:

Background: This gene encodes a member of the ALEX family of proteins which may play a role in tumor suppression. The encoded protein contains a potential N-terminal transmembrane domain and a single Armadillo (arm) repeat. Other proteins containing the arm repeat are involved in development, maintenance of tissue integrity, and tumorigenesis. This gene is closely localized with other family members on the X chromosome. Three transcript variants encoding the same protein have been identified for this gene.

Application Details

Application Notes: ELISA ~~ 1ug/ml~3ng/ml Western blot ~~ 1:500~1000

Purification: Purified

Buffer: Clear, colorless solution in phosphate buffered saline, pH 7.2 .

Storage: Maintain refrigerated at 2-8 deg C for up to 6 months. For long term storage store at -20 deg C in small aliquots to prevent freeze-thaw cycles

Research Area: Cell Structure, Cancer

Restrictions: For Research Use only

Images

ARMCX3 monoclonal antibody (M01), clone 2G3 Western Blot analysis of ARMCX3 expression in COLO 320 HSR ( Cat # L020V1 ). Detection limit for recombinant GST tagged ARMCX3 is approximately 0.1ng/ml as a capture antibody.

anti-Armadillo Repeat Containing, X-Linked 3 (ARMCX3) antibody (Image 2)

Publications

Product: Stelzl, Worm, Lalowski et al.: "A human protein-protein interaction network: a resource for annotating the proteome." in: Cell, Vol. 122, Issue 6, pp. 957-68, 2005 (PubMed).

Olsen, Blagoev, Gnad et al.: "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks." in: Cell, Vol. 127, Issue 3, pp. 635-48, 2006 (PubMed).

Jeronimo, Forget, Bouchard et al.: "Systematic analysis of the protein interaction network for the human transcription machinery reveals the identity of the 7SK capping enzyme." in: Molecular cell, Vol. 27, Issue 2, pp. 262-74, 2007 (PubMed).

Barbe, Lundberg, Oksvold et al.: "Toward a confocal subcellular atlas of the human proteome." in: Molecular & cellular proteomics : MCP, Vol. 7, Issue 3, pp. 499-508, 2008 (PubMed).

Mou, Tapper, Gardner: "The armadillo repeat-containing protein, ARMCX3, physically and functionally interacts with the developmental regulatory factor Sox10." in: The Journal of biological chemistry, Vol. 284, Issue 20, pp. 13629-40, 2009 (PubMed).