Armadillo Repeat Containing, X-Linked 3 (ARMCX3) (AA 278-380) antibody

Details for Product No. ABIN395662, Supplier: Log in to see
Antigen
  • ARMCX3
  • DKFZp459E2029
  • ALEX3
  • dJ545K15.2
  • 1200004E24Rik
  • AI450003
  • armadillo repeat containing, X-linked 3
  • ARMCX3
  • LOC100349702
  • Armcx3
Epitope
AA 278-380
14
10
8
6
3
2
2
1
1
1
1
1
Reactivity
Human
60
23
22
3
3
3
2
2
2
1
Host
Mouse
54
6
Clonality (Clone)
Monoclonal ()
Conjugate
Un-conjugated
3
3
3
2
2
2
1
1
1
1
1
1
1
1
1
1
1
Application
Western Blotting (WB)
45
22
13
6
6
4
2
1
Options
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Immunogen ARMCX3 (NP_057691, 278 a.a. ~ 380 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 K
Clone 2G3
Isotype IgG2a kappa
Specificity ARMCX3 (NP_057691, 278 a.a. ~ 380 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Purification This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
Alternative Name ARMCX3 (ARMCX3 Antibody Abstract)
Background Synonyms: Serine protease inhibitor J6, 47 kDa heat shock protein, Collagen-binding protein, Colligin, Serpin H1,Hsp47, Cbp1, Serpinh1
Molecular Weight 42501 DA
Gene ID 12406
NCBI Accession NP_057691
Research Area Cell Structure, Cancer
Application Notes Western blot = 1:500-1000
Comment

Background: This gene encodes a member of the ALEX family of proteins which may play a role in tumor suppression. The encoded protein contains a potential N-terminal transmembrane domain and a single Armadillo (arm) repeat. Other proteins containing the arm repeat are involved in development, maintenance of tissue integrity, and tumorigenesis. This gene is closely localized with other family members on the X chromosome. Three transcript variants encoding the same protein have been identified for this gene.

Restrictions For Research Use only
Buffer PBS with 0.09% (w/v) sodium azide.
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles
Expiry Date 6 months
Supplier Images
Western Blotting (WB) image for anti-Armadillo Repeat Containing, X-Linked 3 (ARMCX3) (AA 278-380) antibody (ABIN395662) ARMCX3 monoclonal antibody (M01), clone 2G3 Western Blot analysis of ARMCX3 expressio...
Immunohistochemistry (IHC) image for anti-Armadillo Repeat Containing, X-Linked 3 (ARMCX3) (AA 278-380) antibody (ABIN395662) anti-Armadillo Repeat Containing, X-Linked 3 (ARMCX3) (AA 278-380) antibody (Image 2)
Background publications Mou, Tapper, Gardner: "The armadillo repeat-containing protein, ARMCX3, physically and functionally interacts with the developmental regulatory factor Sox10." in: The Journal of biological chemistry, Vol. 284, Issue 20, pp. 13629-40, 2009 (PubMed).

Barbe, Lundberg, Oksvold, Stenius, Lewin, Björling, Asplund, Pontén, Brismar, Uhlén, Andersson-Svahn: "Toward a confocal subcellular atlas of the human proteome." in: Molecular & cellular proteomics : MCP, Vol. 7, Issue 3, pp. 499-508, 2008 (PubMed).

Jeronimo, Forget, Bouchard, Li, Chua, Poitras, Thérien, Bergeron, Bourassa, Greenblatt, Chabot, Poirier, Hughes, Blanchette, Price, Coulombe: "Systematic analysis of the protein interaction network for the human transcription machinery reveals the identity of the 7SK capping enzyme." in: Molecular cell, Vol. 27, Issue 2, pp. 262-74, 2007 (PubMed).

Olsen, Blagoev, Gnad, Macek, Kumar, Mortensen, Mann: "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks." in: Cell, Vol. 127, Issue 3, pp. 635-48, 2006 (PubMed).

Stelzl, Worm, Lalowski, Haenig, Brembeck, Goehler, Stroedicke, Zenkner, Schoenherr, Koeppen, Timm, Mintzlaff, Abraham, Bock, Kietzmann, Goedde, Toksöz, Droege, Krobitsch, Korn, Birchmeier, Lehrach et al.: "A human protein-protein interaction network: a resource for annotating the proteome. ..." in: Cell, Vol. 122, Issue 6, pp. 957-68, 2005 (PubMed).