|+1 404 474 4654|
|+1 888 205 9894 (TF)|
Aldehyde Dehydrogenase 3 Family, Member A1 (ALDH3A1) antibody
|Synonyms||ALDH3A1, ALDH3, ALDHIII, MGC10406, ALDEHYDE DEHYDROGENASE 3, ALDEHYDE DEHYDROGENASE 3I1, ALDH3I1, F10M10.10, F10M10_10|
|5 references available|
|Price||450.00 $ Plus shipping costs $45.00|
|Availability||Will be delivered in 2 to 3 Business Days|
|Immunogen||ALDH3A1 (AAH04370, 1 a.a. ~ 454 a.a) full length recombinant protein with GST tag. MW of the GST tag alone is 26 K|
|Description||Other names: ALDH3, ALDHIII, MGC10406aldehyde dehydrogenase 3 family, memberA1|
|Characteristics||Purified Mouse Monoclonal Antibody (Mab)|
|Specificity||ALDH3A1 (AAH04370, 1 a.a. ~ 454 a.a) full length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.|
|Molecular Weight||50379 DA|
Background: Aldehyde dehydrogenases oxidize various aldehydes to the corresponding acids. They are involved in the detoxification of alcohol-derived acetaldehyde and in the metabolism of corticosteroids, biogenic amines, neurotransmitters, and lipid peroxidation. The enzyme encoded by this gene forms a cytoplasmic homodimer that preferentially oxidizes aromatic and medium-chain (6 carbons or more) saturated and unsaturated aldehyde substrates. It is thought to promote resistance to UV and 4-hydroxy-2-nonenal-induced oxidative damage in the cornea. The gene is located within the Smith-Magenis syndrome region on chromosome 17. Multiple alternatively spliced variants, encoding the same protein, have been identified.
|Application Notes||ELISA ~~ 1ug/ml~3ng/ml|
|Buffer||Clear, colorless solution in phosphate buffered saline, pH 7.2 .|
|Storage||Maintain refrigerated at 2-8 deg C for up to 6 months. For long term storage store at -20 deg C in small aliquots to prevent freeze-thaw cycles|
|Research Area||Metabolism, Cell Structure|
|Restrictions||For Research Use only|
|Detection limit for recombinant GST tagged ALDH3A1 is approximately 1ng/ml as a capture antibody.|
Low, Kiyotani, Mushiroda et al.: "Association study of genetic polymorphism in ABCC4 with cyclophosphamide-induced adverse drug reactions in breast cancer patients." in: Journal of human genetics, Vol. 54, Issue 10, pp. 564-71, 2009 (PubMed).
Bogucka, Giebułtowicz, Zawada et al.: "The oxidation status of ALDH3A1 in human saliva and its correlation with antioxidant capacity measured by ORAC method." in: Acta poloniae pharmaceutica, Vol. 66, Issue 5, pp. 477-82, 2009 (PubMed).
Searles Nielsen, McKean-Cowdin, Farin et al.: "Childhood brain tumors, residential insecticide exposure, and pesticide metabolism genes." in: Environmental health perspectives, Vol. 118, Issue 1, pp. 144-9, 2010 (PubMed).
Davila, Froeling, Tan et al.: "New genetic associations detected in a host response study to hepatitis B vaccine." in: Genes and immunity, Vol. 11, Issue 3, pp. 232-8, 2010 (PubMed).
Rose, Behm, Drgon et al.: "Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score." in: Molecular medicine (Cambridge, Mass.), Vol. 16, Issue 7-8, pp. 247-53, 2010 (PubMed).
|Hosts||Rabbit (24), Goat (3), Mouse (2)|
|Reactivities||Human (27), Mouse (Murine) (8), Rat (Rattus) (7), Cat (Feline) (1), Chicken (1), Cow (Bovine) (1), Dog (Canine) (1)|
|Applications||Western Blotting (WB) (29), ELISA (15), Immunohistochemistry (IHC) (9), Flow Cytometry (FACS) (4), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (4), Immunofluorescence (IF) (3), Immunoprecipitation (IP) (1)|
|Epitopes||C-Term (6), N-Term (6), Internal Region (4), Transcript Variant 2 (2), Center (1)|