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Acylphosphatase 2, Muscle Type (Acyp2) (AA 1-99) antibody

Details for Product No. ABIN395739, Supplier: Login to see
Antigen
  • AcPDro2
  • CG18505
  • Dmel\\CG18505
  • ACYP2
  • acym
  • acyp
  • ACYM
  • ACYP
  • 2310004B09Rik
  • Acyp2
  • Mif-ps1
Epitope
AA 1-99
3
2
1
Reactivity
Human
13
7
6
Host
Mouse
9
4
Clonality (Clone)
Monoclonal ()
Application
Western Blotting (WB)
12
11
7
2
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Immunogen ACYP2 (NP_612457, 1 a.a. ~ 99 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 K
Clone 2H7
Isotype IgG1 kappa
Specificity ACYP2 (NP_612457, 1 a.a. ~ 99 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Purification This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
Alternative Name ACYP2 (Acyp2 Antibody Abstract)
Background Synonyms: Serine protease inhibitor J6, 47 kDa heat shock protein, Collagen-binding protein, Colligin, Serpin H1,Hsp47, Cbp1, Serpinh1
Molecular Weight 11140 DA
Gene ID 12406
NCBI Accession NP_612457
Research Area Cell Structure
Pathways
Application Notes Western blot = 1:500-1000
Comment

Background: Acylphosphatase can hydrolyze the phosphoenzyme intermediate of different membrane pumps, particularly the Ca2+/Mg2+-ATPase from sarcoplasmic reticulum of skeletal muscle. Two isoenzymes have been isolated, called muscle acylphosphatase and erythrocyte acylphosphatase on the basis of their tissue localization. This gene encodes the muscle-type isoform (MT). An increase of the MT isoform is associated with muscle differentiation.

Restrictions For Research Use only
Buffer PBS with 0.09% (w/v) sodium azide.
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles
Expiry Date 6 months
Supplier Images
Western Blotting (WB) image for anti-Acylphosphatase 2, Muscle Type (Acyp2) (AA 1-99) antibody (ABIN395739) Western blot analysis of ACYP2 over-expressed 293 cell line, cotransfected with ACYP2...
Immunohistochemistry (IHC) image for anti-Acylphosphatase 2, Muscle Type (Acyp2) (AA 1-99) antibody (ABIN395739) anti-Acylphosphatase 2, Muscle Type (Acyp2) (AA 1-99) antibody (Image 2)
Background publications Rose, Behm, Drgon et al.: "Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score." in: Molecular medicine (Cambridge, Mass.), Vol. 16, Issue 7-8, pp. 247-53, 2010 (PubMed).

Yoshida, Kato, Yokoi et al.: "Association of genetic variants with hemorrhagic stroke in Japanese individuals." in: International journal of molecular medicine, Vol. 25, Issue 4, pp. 649-56, 2010 (PubMed).

Oguri, Kato, Yokoi et al.: "Assessment of a polymorphism of SDK1 with hypertension in Japanese Individuals." in: American journal of hypertension, Vol. 23, Issue 1, pp. 70-7, 2009 (PubMed).

Calamai, Tartaglia, Vendruscolo et al.: "Mutational analysis of the aggregation-prone and disaggregation-prone regions of acylphosphatase." in: Journal of molecular biology, Vol. 387, Issue 4, pp. 965-74, 2009 (PubMed).

Ng, Hu, Hu et al.: "Replication of a genome-wide case-control study of esophageal squamous cell carcinoma." in: International journal of cancer. Journal international du cancer, Vol. 123, Issue 7, pp. 1610-5, 2008 (PubMed).