butyrophilin, Subfamily 2, Member A1 (BTN2A1) antibody

Antigen: butyrophilin, Subfamily 2, Member A1 (BTN2A1)

Synonyms: BT, BTN, BTF1, BT2.1, DJ3E1.1, BK14H9.1, FLJ36567, Btn, BTN1A1, TVC, BTN2A1, btf1, bt2.1, BTN2A2, DKFZp459K228

Clonality: Monoclonal (3A1)

Host: Mouse

Reactivity: Human

Application: ELISA

Certificates: ISO 9001:2008

Catalog no.: ABIN395751

Additional Information

Alternative name: BTN2A1

Gene ID: 11120

Immunogen: BTN2A1 (AAH16661, 1 a.a. ~ 335 a.a) full length recombinant protein with GST tag. MW of the GST tag alone is 26 K

Isotype: IgG2a kappa

Clone: 3A1

Description: Other names: BT2.1, BTF1 butyrophilin, subfamily 2, member A1

Characteristics: Purified Mouse Monoclonal Antibody (Mab)

Specificity: BTN2A1 (AAH16661, 1 a.a. ~ 335 a.a) full length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Molecular Weight: 60004 DA

Comments:

Background: This gene is a member of the BTN2 subfamily of genes, which encode proteins belonging to the butyrophilin protein family. The gene is located in a cluster on chromosome 6, consisting of seven genes belonging to the expanding B7/butyrophilin-like group, a subset of the immunoglobulin gene superfamily. The encoded protein is an integral plasma membrane B box protein involved in lipid, fatty-acid and sterol metabolism.

Application Details

Application Notes: ELISA ~~ 1ug/ml~3ng/ml

Purification: Purified

Buffer: Clear, colorless solution in phosphate buffered saline, pH 7.2 .

Storage: Maintain refrigerated at 2-8 deg C for up to 6 months. For long term storage store at -20 deg C in small aliquots to prevent freeze-thaw cycles

Research Area: Cell Structure, Metabolism

Restrictions: For Research Use only

Images

Detection limit for recombinant GST tagged BTN2A1 is approximately 1ng/ml as a capture antibody.

Publications

Product: Strausberg, Feingold, Grouse et al.: "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 99, Issue 26, pp. 16899-903, 2002 (PubMed).

Mungall, Palmer, Sims et al.: "The DNA sequence and analysis of human chromosome 6." in: Nature, Vol. 425, Issue 6960, pp. 805-11, 2003 (PubMed).

Ota, Suzuki, Nishikawa et al.: "Complete sequencing and characterization of 21,243 full-length human cDNAs." in: Nature genetics, Vol. 36, Issue 1, pp. 40-5, 2003 (PubMed).

Malcherek, Mayr, Roda-Navarro et al.: "The B7 homolog butyrophilin BTN2A1 is a novel ligand for DC-SIGN." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 179, Issue 6, pp. 3804-11, 2007 (PubMed).

Benyamin, McRae, Zhu et al.: "Variants in TF and HFE explain approximately 40% of genetic variation in serum-transferrin levels." in: American journal of human genetics, Vol. 84, Issue 1, pp. 60-5, 2009 (PubMed).