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butyrophilin, Subfamily 2, Member A1 (BTN2A1) (AA 1-335) antibody

Details for Product No. ABIN395751, Supplier: Log in to see
Antigen
  • BTN2A1
  • btf1
  • bt2.1
  • BTN2A2
  • BK14H9.1
  • BT2.1
  • BTF1
  • DJ3E1.1
Epitope
AA 1-335
18
16
3
2
1
1
1
Reactivity
Human
37
2
2
1
Host
Mouse
34
3
Clonality (Clone)
Monoclonal ()
Conjugate
Un-conjugated
2
2
2
2
2
2
1
Application
ELISA
29
21
1
1
Supplier
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Immunogen BTN2A1 (AAH16661, 1 a.a. ~ 335 a.a) full length recombinant protein with GST tag. MW of the GST tag alone is 26 K
Clone 3A1
Isotype IgG2a kappa
Specificity BTN2A1 (AAH16661, 1 a.a. ~ 335 a.a) full length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Purification This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
Alternative Name BTN2A1 (BTN2A1 Antibody Abstract)
Background Synonyms: Serine protease inhibitor J6, 47 kDa heat shock protein, Collagen-binding protein, Colligin, Serpin H1,Hsp47, Cbp1, Serpinh1
Molecular Weight 60004 DA
Gene ID 12406
Research Area Cell Structure, Metabolism
Application Notes ELISA ~~ 1ug/ml~3ng/ml
Comment

Background: This gene is a member of the BTN2 subfamily of genes, which encode proteins belonging to the butyrophilin protein family. The gene is located in a cluster on chromosome 6, consisting of seven genes belonging to the expanding B7/butyrophilin-like group, a subset of the immunoglobulin gene superfamily. The encoded protein is an integral plasma membrane B box protein involved in lipid, fatty-acid and sterol metabolism.

Restrictions For Research Use only
Buffer PBS with 0.09% (w/v) sodium azide.
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles
Expiry Date 6 months
Supplier Images
ELISA image for anti-butyrophilin, Subfamily 2, Member A1 (BTN2A1) (AA 1-335) antibody (ABIN395751) Detection limit for recombinant GST tagged BTN2A1 is approximately 1 ng/mL as a captu...
Background publications Benyamin, McRae, Zhu et al.: "Variants in TF and HFE explain approximately 40% of genetic variation in serum-transferrin levels." in: American journal of human genetics, Vol. 84, Issue 1, pp. 60-5, 2009 (PubMed).

Malcherek, Mayr, Roda-Navarro et al.: "The B7 homolog butyrophilin BTN2A1 is a novel ligand for DC-SIGN." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 179, Issue 6, pp. 3804-11, 2007 (PubMed).

Ota, Suzuki, Nishikawa et al.: "Complete sequencing and characterization of 21,243 full-length human cDNAs. ..." in: Nature genetics, Vol. 36, Issue 1, pp. 40-5, 2003 (PubMed).

Mungall, Palmer, Sims et al.: "The DNA sequence and analysis of human chromosome 6. ..." in: Nature, Vol. 425, Issue 6960, pp. 805-11, 2003 (PubMed).

Strausberg, Feingold, Grouse et al.: "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. ..." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 99, Issue 26, pp. 16899-903, 2002 (PubMed).