Did you know that you can buy products from over 140 different suppliers from us?

Tryptophanyl-tRNA Synthetase, WARS (WARS) antibody

Details for Product No. ABIN395766
Request Want additional data for this product?

The Independent Validation Initiative strives to provide you with high quality data. Find out more

Antigen
Synonyms IFI53, IFP53, GAMMA-2, WRS, TrpRS, WARS
Reactivity
Human
(26), (3), (3)
Host
Mouse
(22), (7)
Clonality (Clone)
Monoclonal ()
Conjugate
Un-conjugated
(2), (2), (2), (2), (2), (2)
Application
Immunofluorescence (IF), Western Blotting (WB)
(28), (19), (9), (5), (4), (3), (3), (2)
Pubmed 5 references available
Quantity 0.1 mg
Options
Shipping to United States (Change)
Availability Will be delivered in 2 to 3 Business Days
Catalog No. ABIN395766
450.00 $
Plus shipping costs $45.00

Order hotline:

  • +1 404 474 4654
  • +1 888 205 9894 (TF)
Immunogen WARS (NP_004175, 50 a.a. ~ 150 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 K
Clone 3A12
Isotype IgG2a kappa
Specificity WARS (NP_004175, 50 a.a. ~ 150 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Purification This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
Alternative Name WARS
Background Synonyms: Serine protease inhibitor J6, 47 kDa heat shock protein, Collagen-binding protein, Colligin, Serpin H1,Hsp47, Cbp1, Serpinh1
Molecular Weight 53165 DA
Gene ID 12406
UniProt NP_004175
Research Area Cell Structure
Application Notes Western blot = 1:500-1000
Comment

Background: Aminoacyl-tRNA synthetases catalyze the aminoacylation of tRNA by their cognate amino acid. Because of their central role in linking amino acids with nucleotide triplets contained in tRNAs, aminoacyl-tRNA synthetases are thought to be among the first proteins that appeared in evolution. Two forms of tryptophanyl-tRNA synthetase exist, a cytoplasmic form, named WARS, and a mitochondrial form, named WARS2. Tryptophanyl-tRNA synthetase (WARS) catalyzes the aminoacylation of tRNA(trp) with tryptophan and is induced by interferon. Tryptophanyl-tRNA synthetase belongs to the class I tRNA synthetase family. Four transcript variants encoding two different isoforms have been found for this gene.

Restrictions For Research Use only
Concentration 1 mg/ml
Buffer PBS with 0.09% (w/v) sodium azide.
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles
Expiry Date 6 months
Supplier Images
anti-Tryptophanyl-tRNA Synthetase, WARS (WARS) antibody Immunofluorescence of monoclonal antibody to WARS on HeLa cell (antibody concentration 10 µg/mL). WARS monoclonal antibody (M02), clone 3A12 Western Blot analysis of WARS expression in HeLa.
anti-Tryptophanyl-tRNA Synthetase, WARS (WARS) antibody (2) anti-Tryptophanyl-tRNA Synthetase, WARS (WARS) antibody (Image 2)
Background publications Wang, Mao, Zhao et al.: "Increased TTS abrogates IDO-mediated CD4(+) T cells suppression in patients with Graves' disease." in: Endocrine, Vol. 36, Issue 1, pp. 119-25, 2009 (PubMed).

Bhattacharyya, Ghosh, Hansia et al.: "Allostery and conformational free energy changes in human tryptophanyl-tRNA synthetase from essential dynamics and structure networks." in: Proteins, Vol. 78, Issue 3, pp. 506-17, 2010 (PubMed).

Ghanipour, Jirström, Pontén et al.: "The prognostic significance of tryptophanyl-tRNA synthetase in colorectal cancer." in: Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, Vol. 18, Issue 11, pp. 2949-56, 2009 (PubMed).

Talmud, Drenos, Shah et al.: "Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip." in: American journal of human genetics, Vol. 85, Issue 5, pp. 628-42, 2009 (PubMed).

Bailey, Xie, Do et al.: "Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study." in: Diabetes Care, Vol. 33, Issue 10, pp. 2250-3, 2010 (PubMed).

Request Want additional data for this product?

The Independent Validation Initiative strives to provide you with high quality data. Find out more

Catalog No. ABIN395766
450.00 $
Plus shipping costs $45.00

Order hotline:

  • +1 404 474 4654
  • +1 888 205 9894 (TF)
Validation Images
Did you look for something else?
back to top