Prefoldin Subunit 3 (PFDN3) (AA 1-198) antibody

Details for Product No. ABIN395932
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Antigen
Synonyms DDBDRAFT_0218815, DDBDRAFT_0237722, DDB_0218815, DDB_0237722, PFD3, PFDN3, VBP-1
Epitope
AA 1-198
(6), (6), (2), (2), (1)
Reactivity
Human
(31), (2), (2)
Host
Mouse
(22), (9)
Clonality (Clone)
Monoclonal ()
Conjugate
Un-conjugated
(1), (1), (1), (1), (1), (1)
Application
Western Blotting (WB)
(30), (12), (10), (9), (6), (3), (2), (2)
Pubmed 5 references available
Quantity 0.1 mg
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Catalog No. ABIN395932
450.00 $
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Immunogen VBP1 (AAH46094, 1 a.a. ~ 198 a.a) full length recombinant protein with GST tag. MW of the GST tag alone is 26 K
Clone 3D11
Isotype IgG1 kappa
Specificity VBP1 (AAH46094, 1 a.a. ~ 198 a.a) full length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Purification This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
Alternative Name VBP1
Background Synonyms: Serine protease inhibitor J6, 47 kDa heat shock protein, Collagen-binding protein, Colligin, Serpin H1,Hsp47, Cbp1, Serpinh1
Molecular Weight 22658 DA
Gene ID 12406
Research Area Cell Structure
Application Notes Western blot = 1:500-1000
Comment

Background: The protein encoded by this gene interacts with the Von Hippel-Lindau protein to form an intracellular complex. Because it functions as a chaperone protein, it is suspected that it may play a role in the transport of the Von Hippel-Lindau protein from the perinuclear granules to the nucleus or cytoplasm.

Restrictions For Research Use only
Concentration 1mg/ml
Buffer PBS with 0.09% (w/v) sodium azide.
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles
Expiry Date 6 months
Supplier Images
anti-Prefoldin Subunit 3 (PFDN3) (AA 1-198) antibody VBP1 monoclonal antibody (M01), clone 3D11 Western Blot analysis of VBP1 expression in HL-60 on formalin-fixed paraffin-embedded human breast cancer tissue (antibody concentration 5 µg/mL).
anti-Prefoldin Subunit 3 (PFDN3) (AA 1-198) antibody (2) anti-Prefoldin Subunit 3 (PFDN3) (AA 1-198) antibody (Image 2)
Background publications Kralovics, Skoda: "Molecular pathogenesis of Philadelphia chromosome negative myeloproliferative disorders." in: Blood reviews, Vol. 19, Issue 1, pp. 1-13, 2004 (PubMed).

Ross, Grafham, Coffey et al.: "The DNA sequence of the human X chromosome." in: Nature, Vol. 434, Issue 7031, pp. 325-37, 2005 (PubMed).

Talmud, Drenos, Shah et al.: "Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes." in: Genome research, Vol. 16, Issue 1, pp. 55-65, 2006 (PubMed).

Mousnier, Kubat, Massias-Simon et al.: "von Hippel Lindau binding protein 1-mediated degradation of integrase affects HIV-1 gene expression at a postintegration step." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 104, Issue 34, pp. 13615-20, 2007 (PubMed).

Sowa, Bennett, Gygi et al.: "Defining the human deubiquitinating enzyme interaction landscape." in: Cell, Vol. 138, Issue 2, pp. 389-403, 2009 (PubMed).

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