RHOH (AA 1-192) antibody

Details for Product No. ABIN395948
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Synonyms ARHH, TTF, 5830400A04Rik, AU019774, Arhh
AA 1-192
(27), (15), (5), (4), (1), (1), (1)
(48), (15), (15), (1)
(42), (6)
Clonality (Clone)
Monoclonal ()
(2), (2), (2), (2), (2), (2)
(41), (36), (15), (10), (4), (3), (1), (1)
Pubmed 5 references available
Quantity 0.1 mg
Shipping to United States ( )
Availability Will be delivered in 8 to 11 Business Days
Immunogen RHOH (AAH14261, 1 a.a. ~ 192 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 K
Clone 3D3
Isotype IgG2a kappa
Specificity RHOH (AAH14261, 1 a.a. ~ 192 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Purification This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
Background Synonyms: Serine protease inhibitor J6, 47 kDa heat shock protein, Collagen-binding protein, Colligin, Serpin H1,Hsp47, Cbp1, Serpinh1
Molecular Weight 21331 DA
Gene ID 12406
Research Area Cancer, Cell Structure
Application Notes ELISA ~~ 1ug/ml~3ng/ml

Background: The protein encoded by this gene is a member of the Ras superfamily of small GTPases. Expression of a chimeric transcript of LAZ3 and this gene has been reported as a result of the translocation t(3,4) in non-Hodgkin's lymphomas. This gene encodes a small G-like protein, and unlike most other small G proteins which are expressed ubiquitously, this gene is transcribed only in hemopoietic cells.

Restrictions For Research Use only
Buffer PBS with 0.09% (w/v) sodium azide.
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles
Expiry Date 6 months
Supplier Images
ELISA image for anti-RHOH (AA 1-192) antibody (ABIN395948) Detection limit for recombinant GST tagged RHOH is approximately 1 ng/mL as a capture...
Background publications Rose, Behm, Drgon et al.: "Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score." in: Molecular medicine (Cambridge, Mass.), Vol. 16, Issue 7-8, pp. 247-53, 2010 (PubMed).

Schmidt-Mende, Geering, Yousefi et al.: "Lysosomal degradation of RhoH protein upon antigen receptor activation in T but not B cells." in: European journal of immunology, Vol. 40, Issue 2, pp. 525-9, 2010 (PubMed).

Sanchez-Aguilera, Rattmann, Drew et al.: "Involvement of RhoH GTPase in the development of B-cell chronic lymphocytic leukemia." in: Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K, Vol. 24, Issue 1, pp. 97-104, 2010 (PubMed).

Daryadel, Yousefi, Troi et al.: "RhoH/TTF negatively regulates leukotriene production in neutrophils." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 182, Issue 10, pp. 6527-32, 2009 (PubMed).

Iwasaki, Katsumi, Kiyoi et al.: "Prognostic implication and biological roles of RhoH in acute myeloid leukaemia." in: European journal of haematology, Vol. 81, Issue 6, pp. 454-60, 2008 (PubMed).

Catalog No. ABIN395948
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