RHOH antibody

Details for Product No. ABIN395948
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Antigen
Synonyms TTF, ARHH, Arhh, AU019774, 5830400A04Rik
Reactivity
Human
(25), (13), (13)
Host
Mouse
(20), (5)
Clonality (Clone)
Monoclonal ()
Application
ELISA
(21), (21), (12), (5), (4), (4)
Pubmed 5 references available
Catalog no. ABIN395948
Quantity 0.1 mg
Price
450.00 $   Plus shipping costs $45.00
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  • +1 404 474 4654
  • +1 888 205 9894 (TF)
Immunogen RHOH (AAH14261, 1 a.a. ~ 192 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 K
Clone 3D3
Isotype IgG2a kappa
Specificity RHOH (AAH14261, 1 a.a. ~ 192 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Purification This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
Background Synonyms: Serine protease inhibitor J6, 47 kDa heat shock protein, Collagen-binding protein, Colligin, Serpin H1,Hsp47, Cbp1, Serpinh1
Molecular Weight 21331 DA
Gene ID 12406
Research Area Cancer, Cell Structure
Application Notes ELISA ~~ 1ug/ml~3ng/ml
Comment

Background: The protein encoded by this gene is a member of the Ras superfamily of small GTPases. Expression of a chimeric transcript of LAZ3 and this gene has been reported as a result of the translocation t(3,4) in non-Hodgkin's lymphomas. This gene encodes a small G-like protein, and unlike most other small G proteins which are expressed ubiquitously, this gene is transcribed only in hemopoietic cells.

Restrictions For Research Use only
Buffer PBS with 0.09% (w/v) sodium azide.
Preservative Sodium azide
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles
Expiry Date 6 months
Supplier Images
anti-RHOH antibody Detection limit for recombinant GST tagged RHOH is approximately 1 ng/mL as a capture antibody.
Background publications Iwasaki, Katsumi, Kiyoi et al.: "Prognostic implication and biological roles of RhoH in acute myeloid leukaemia." in: European journal of haematology, Vol. 81, Issue 6, pp. 454-60, 2008 (PubMed).

Daryadel, Yousefi, Troi et al.: "RhoH/TTF negatively regulates leukotriene production in neutrophils." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 182, Issue 10, pp. 6527-32, 2009 (PubMed).

Sanchez-Aguilera, Rattmann, Drew et al.: "Involvement of RhoH GTPase in the development of B-cell chronic lymphocytic leukemia." in: Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K, Vol. 24, Issue 1, pp. 97-104, 2010 (PubMed).

Schmidt-Mende, Geering, Yousefi et al.: "Lysosomal degradation of RhoH protein upon antigen receptor activation in T but not B cells." in: European journal of immunology, Vol. 40, Issue 2, pp. 525-9, 2010 (PubMed).

Rose, Behm, Drgon et al.: "Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score." in: Molecular medicine (Cambridge, Mass.), Vol. 16, Issue 7-8, pp. 247-53, 2010 (PubMed).

Hosts (20), (5)
Reactivities (25), (13), (13)
Applications (21), (21), (12), (5), (4), (4)
Epitopes (10), (4), (1), (1), (1), (1)
Request Want additional data for this product?

The Independent Validation Initiative strives to provide you with high quality data. Find out more

Order hotline:

  • +1 404 474 4654
  • +1 888 205 9894 (TF)
Validation Images
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